Evidence map›Paper›PMID 34328441›Full record

ArticleJMIR mHealth and uHealth2021

Predicting Depressive Symptom Severity Through Individuals' Nearby Bluetooth Device Count Data Collected by Mobile Phones: Preliminary Longitudinal Study.

Yuezhou Zhang, Amos A Folarin, Shaoxiong Sun, Nicholas Cummins, Yatharth Ranjan, Zulqarnain Rashid, Pauline Conde, Callum Stewart, Petroula Laiou, Faith Matcham and 14 more

Abstract read
In one paragraph

Article in JMIR mHealth and uHealth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Systematic Review of Location Data for Depression Prediction.International journal of environmental research and public health · 2023
    Pooled it
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  18. Beyond Detection: Towards Actionable Sensing Research in Clinical Mental Healthcare.Proceedings of the ACM on interactive, mobile, wearable and ubiquitous technologies · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yuezhou ZhangDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-4817-3835
Amos A FolarinDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-0333-1927
Shaoxiong SunDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-3652-5266
Nicholas CumminsDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-1178-917X
Yatharth RanjanDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-3079-3120
Zulqarnain RashidDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-6843-9920
Pauline CondeDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-0513-0915
Callum StewartDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0001-9947-8677
Petroula LaiouDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-5798-6961
Faith MatchamDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-4055-904X
Carolin OetzmannDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-1480-917X
Femke LamersDepartment of Psychiatry, Amsterdam Public Health Research Institute and Amsterdam Neuroscience, Amsterdam University Medical Centre, Vrije Universiteit and GGZ InGeest, Amsterdam, Netherlands.ORCID 0000-0003-4344-5766
Sara SiddiTeaching Research and Innovation Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona, Spain.ORCID 0000-0002-1494-9028
Sara SimblettDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-8075-8238
Aki RintalaCenter for Contextual Psychiatry, Department of Neurosciences, Katholieke Universiteit Leuven, Leuven, Belgium.ORCID 0000-0002-0066-4697
David C MohrCenter for Behavioral Intervention Technologies, Department of Preventive Medicine, Northwestern University, Evanston, IL, United States.ORCID 0000-0002-5443-7596
Inez Myin-GermeysCenter for Contextual Psychiatry, Department of Neurosciences, Katholieke Universiteit Leuven, Leuven, Belgium.ORCID 0000-0002-3731-4930
Til WykesNIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, United Kingdom.ORCID 0000-0002-5881-8003
Josep Maria HaroTeaching Research and Innovation Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona, Spain.ORCID 0000-0002-3984-277X
Brenda W J H PenninxDepartment of Psychiatry, Amsterdam Public Health Research Institute and Amsterdam Neuroscience, Amsterdam University Medical Centre, Vrije Universiteit and GGZ InGeest, Amsterdam, Netherlands.ORCID 0000-0001-7779-9672
Vaibhav A NarayanJanssen Research and Development LLC, Titusville, NJ, United States.ORCID 0000-0001-6092-5150
Peter AnnasH Lundbeck A/S, Copenhagen, Denmark.ORCID 0000-0003-0576-765X
Matthew HotopfNIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, United Kingdom.ORCID 0000-0002-3980-4466
Richard J B DobsonDepartment of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0003-4224-9245

Funding

Technology Enabled Services for Coordinated Care of Depression in Healthcare SettingsP50MH119029 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DAVID CURTIS MOHR, Jessica Lee Schleider · 2020 to 2026
$10.7M
LifeSense: Transforming Behavioral Assessment of Depression Using Personal Sensing TechnologyR01MH111610 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KORDING, KONRAD P., MOHR, DAVID CURTIS · 2017 to 2020
$3.2M
British Heart FoundationChief Scientist OfficeMedical Research Council MC_PC_17214NIMH NIH HHS P50 MH119029NIMH NIH HHS R01 MH111610Wellcome Trust
6 · The paper itself

Abstract

backgroundResearch in mental health has found associations between depression and individuals' behaviors and statuses, such as social connections and interactions, working status, mobility, and social isolation and loneliness. These behaviors and statuses can be approximated by the nearby Bluetooth device count (NBDC) detected by Bluetooth sensors in mobile phones.

objectiveThis study aimed to explore the value of the NBDC data in predicting depressive symptom severity as measured via the 8-item Patient Health Questionnaire (PHQ-8).

methodsThe data used in this paper included 2886 biweekly PHQ-8 records collected from 316 participants recruited from three study sites in the Netherlands, Spain, and the United Kingdom as part of the EU Remote Assessment of Disease and Relapse-Central Nervous System (RADAR-CNS) study. From the NBDC data 2 weeks prior to each PHQ-8 score, we extracted 49 Bluetooth features, including statistical features and nonlinear features for measuring the periodicity and regularity of individuals' life rhythms. Linear mixed-effect models were used to explore associations between Bluetooth features and the PHQ-8 score. We then applied hierarchical Bayesian linear regression models to predict the PHQ-8 score from the extracted Bluetooth features.

resultsA number of significant associations were found between Bluetooth features and depressive symptom severity. Generally speaking, along with depressive symptom worsening, one or more of the following changes were found in the preceding 2 weeks of the NBDC data: (1) the amount decreased, (2) the variance decreased, (3) the periodicity (especially the circadian rhythm) decreased, and (4) the NBDC sequence became more irregular. Compared with commonly used machine learning models, the proposed hierarchical Bayesian linear regression model achieved the best prediction metrics (R

conclusionsOur statistical results indicate that the NBDC data have the potential to reflect changes in individuals' behaviors and statuses concurrent with the changes in the depressive state. The prediction results demonstrate that the NBDC data have a significant value in predicting depressive symptom severity. These findings may have utility for the mental health monitoring practice in real-world settings.

Indexed as

Cell PhoneDepressionBayes TheoremHumansLongitudinal StudiesSocial IsolationBluetoothdepressiondigital biomarkersdigital healthdigital phenotypinghierarchical Bayesian modelmental healthmHealthmobile healthmonitoring

Identifiers

PMID34328441
PMCPMC8367113

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.