ReviewJMIR medical informatics2021
The Fast Health Interoperability Resources (FHIR) Standard: Systematic Literature Review of Implementations, Applications, Challenges and Opportunities.
Review in JMIR medical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 122 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Heart rate variability as a dual-use digital biomarker: integrating clinical, AI, and operational perspectives on human performance and resilience.BMC cardiovascular disorders · 2026Pooled it
- Artificial Intelligence Platform Architecture for Hospital Systems: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Enhancing Interoperability for a Sustainable, Patient-Centric Health Care Value Chain: Systematic Review for Taxonomy Development.Journal of medical Internet research · 2025Pooled it
- Electronic Health Record and Semantic Issues Using Fast Healthcare Interoperability Resources: Systematic Mapping Review.Journal of medical Internet research · 2024Pooled it
- A Systematic Review of Electronic Medical Record Driven Quality Measurement and Feedback Systems.International journal of environmental research and public health · 2022Pooled it
- A Remote Patient Monitoring System With Feedback Mechanisms Using a Smartwatch: Concept, Implementation, and Evaluation Based on the activeDCM Randomized Controlled Trial.JMIR mHealth and uHealth · 2024Trial
- Intelligent Real-Time Healthcare and Biomedical Monitoring Systems: A Narrative Review of AI, IoT, and Emerging Technologies.Bioengineering (Basel, Switzerland) · 2026Review
- A comparison of Fast Healthcare Interoperability Resources and Observational Medical Mutcomes Partnership electronic health record data within the All of Us Research Program.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- When Markets Shape AI Mental Health Self-Management Tools: Consequences for Serious Mental Illness.JMIR mental health · 2026Article
- Public Reporting Systems in Health Care and the Underconceptualized Technical Substrate, a Core Information Systems Dimension: Scoping Review.JMIR medical informatics · 2026Article
- Digital Rhythm Surveillance After Postoperative Atrial Fibrillation in Cancer Survivors: A Cardio-Oncology Survivorship Pathway.Medicina (Kaunas, Lithuania) · 2026Review
- Clinical Laboratory Terminology Standardization for Semantic Interoperability Using a Large Language Model-Based Agent: Methodological Study.Journal of medical Internet research · 2026Article
- The AI-Driven Healthcare Value Framework-Rethinking Traditional Care Models in the Age of Automation.Healthcare (Basel, Switzerland) · 2026Article
- Lessons From Building a Large, Public HIV-Related Database in Support of the Ending the HIV Epidemic in the US Initiative.JMIR formative research · 2026Article
- PAUSE-Agents: A Clinician-in-the-Loop Multi-Agent AI Pipeline for ICU-to-Ward Handoff Briefs.medRxiv : the preprint server for health sciences · 2026Article
- Agentic AI for interdisciplinary clinical decision support in high-stakes care.JHEP reports : innovation in hepatology · 2026Article
- Enabling interoperability across disparate health data sources using Large Language Models.PLOS digital health · 2026Article
- Artificial intelligence in chronic kidney disease: Early detection, risk prediction, and personalized treatment strategies.World journal of nephrology · 2026Review
- Telemedicine documentation in neurology and telestroke: a global scoping review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Unique Digital Images as Incentives in Clinical Trials: A Digital Shift Toward Meaningful Participation.Journal of medical Internet research · 2026Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInformation technology has shifted paper-based documentation in the health care sector into a digital form, in which patient information is transferred electronically from one place to another. However, there remain challenges and issues to resolve in this domain owing to the lack of proper standards, the growth of new technologies (mobile devices, tablets, ubiquitous computing), and health care providers who are reluctant to share patient information. Therefore, a solid systematic literature review was performed to understand the use of this new technology in the health care sector. To the best of our knowledge, there is a lack of comprehensive systematic literature reviews that focus on Fast Health Interoperability Resources (FHIR)-based electronic health records (EHRs). In addition, FHIR is the latest standard, which is in an infancy stage of development. Therefore, this is a hot research topic with great potential for further research in this domain.
objectiveThe main aim of this study was to explore and perform a systematic review of the literature related to FHIR, including the challenges, implementation, opportunities, and future FHIR applications.
methodsIn January 2020, we searched articles published from January 2012 to December 2019 via all major digital databases in the field of computer science and health care, including ACM, IEEE Explorer, Springer, Google Scholar, PubMed, and ScienceDirect. We identified 8181 scientific articles published in this field, 80 of which met our inclusion criteria for further consideration.
resultsThe selected 80 scientific articles were reviewed systematically, and we identified open questions, challenges, implementation models, used resources, beneficiary applications, data migration approaches, and goals of FHIR.
conclusionsThe literature analysis performed in this systematic review highlights the important role of FHIR in the health care domain in the near future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.