ReviewCancer science2021
Current progress and future perspectives of research on intravascular large B-cell lymphoma.
Review in Cancer science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- Primary Endometrial Lymphomas: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Intravascular Large B-Cell Lymphoma Presenting as Recurrent Cryptogenic Strokes: A Diagnostic Challenge.Case reports in hematology · 2026Article
- Diffuse FDG uptake of bilateral renal cortex in intravascular large B-cell lymphoma.Radiology case reports · 2026Article
- Acquired immune deficiency syndrome-related intravascular large B-cell lymphoma primarily arising from lymph nodes: a case report.Frontiers in oncology · 2026Article
- Recent advances in understanding and management of intravascular large B-cell lymphoma.Japanese journal of clinical oncology · 2025Review
- Evaluation of clinical biomarkers for differential diagnosis of intravascular lymphoma and Still's disease.Scientific reports · 2025Article
- Simultaneous intravascular large B‑cell lymphoma and papillary thyroid carcinoma: A case report.Molecular and clinical oncology · 2025Article
- Cognitive Dysfunction as an Initial Manifestation of Rheumatoid Arthritis-associated Intravascular Large B-cell Lymphoma.Internal medicine (Tokyo, Japan) · 2025Review
- CT-Imaging Manifestations and Diagnostic Insights in Pulmonary Intravascular Large B-Cell Lymphoma: A Case Series and Literature Review.Cancer reports (Hoboken, N.J.) · 2025Review
- Intravascular large B-cell lymphoma of the central nervous system with renal involvement: a case report and literature review.Frontiers in oncology · 2025Article
- Intravascular large B‑cell lymphoma diagnosed by skin biopsy from cherry angioma: A case report.Molecular and clinical oncology · 2024Article
- Optimizing random skin biopsies: a review of techniques and indications for intravascular large B-cell lymphoma.International journal of hematology · 2024Review
- Intravascular Lymphoma as a Cause of Recurrent Strokes - Case Report and Review of the Literature.The Neurohospitalist · 2023Article
- Characteristics of Renal Intravascular Large B-cell Lymphoma.Kidney international reports · 2023Article
- Fever of unknown origin characterized by acute kidney injury and nephrotic syndrome diagnosed as intravascular large B-cell lymphoma of kidney: case report and literature review.International journal of clinical and experimental pathology · 2023Article
- Intravascular Large B-Cell Lymphoma in Acute Hypoxic Respiratory Failure.Case reports in critical care · 2023Article
- Intravascular Large B Cell Lymphoma with CNS Involvement Successfully Treated with High-Dose Methotrexate and High-Dose Ara-C Based CNS-Directed Chemoimmunotherapy Alternating with Anthracycline Based Chemoimmunotherapy.Blood and lymphatic cancer : targets and therapy · 2022Article
- Current progress and future perspectives of research on intravascular large B-cell lymphoma.Cancer science · 2021Review
- Recommendations for an Approach to Random Skin Biopsy in the Diagnosis of Intravascular B-Cell Lymphoma.Journal of cutaneous medicine and surgeryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravascular large B-cell lymphoma is a rare disease of the large B cells characterized by selective growth in the lumina of small vessels in systemic organs. Since first reported in 1959, the difficulty of obtaining sufficient tumor cells from biopsy specimens has hampered the elucidation of its underlying biology. Recent progress using xenograft models and plasma cell-free DNA has uncovered genetic features that are similar to those of activated B-cell type diffuse large B-cell lymphoma, including MYD88 and CD79B mutations and frequent alterations in immune check point-related genes such as PD-L1 and PD-L2. Given the improvement in clinical outcomes and a higher risk of secondary central nervous system (CNS) involvement in the rituximab era, a phase 2 trial of R-CHOP combined with high-dose methotrexate and intrathecal chemotherapy as a CNS-oriented therapy has been conducted. This trial, the PRIMEUR-IVL study, has displayed good progression-free survival and a low cumulative incidence of secondary CNS involvement. Long-term follow-up within this trial is still ongoing. Further understanding of the pathophysiology of the disease and improvements in clinical outcomes are still needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.