Evidence map›Paper›PMID 34327736›Full record

ArticleBritish journal of clinical pharmacology2022

Making pharmaceutical companies report what matters about innovation.

Adam Cohen, Rebecca Ultee, Glenn van Veldhoven

Abstract read
In one paragraph

Article in British journal of clinical pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Repurposing biosimilars, rethinking costs: a framework for sustainable drug pricing for repurposed bevacizumab for intravitreal injections.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Making pharmaceutical companies report what matters about innovation.British journal of clinical pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam CohenLeiden University Medical Centre, Leiden University, Leiden, The Netherlands.ORCID 0000-0001-7452-6222
Rebecca UlteeLeiden Academic Centre of Drug Research, Leiden, The Netherlands.ORCID 0000-0002-1855-5261
Glenn van VeldhovenLeiden Academic Centre of Drug Research, Leiden, The Netherlands.ORCID 0000-0002-0920-8284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a lack of transparency about the cost of innovation of the pharmaceutical industry even though these costs are claimed to be the major driver for high prices for medicines. This is reflected by annual reports of the major pharmaceutical firms that contain a low number of pages on innovation and its detailed costs in comparison with pages about remuneration of executives where the detail is excessive. This disbalance provides an objective view of the transparency priorities of a company and has the potential to shift this focus in favour of transparent and detailed information on the cost of innovation by adjusting the regulation for financial reporting.

Indexed as

Drug IndustryHumansPharmaceutical PreparationsPharmaceutical Preparationsinnovationpharmaceutical industryremunerationtransparency

Identifiers

PMID34327736
PMCPMC9292238

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.