Evidence map›Paper›PMID 34327649›Full record

ArticleThe international journal of cardiovascular imaging2021

Prognostic impact of non-improvement of global longitudinal strain in patients with revascularized acute myocardial infarction.

Jan Erik Otterstad, Ingvild Billehaug Norum, Vidar Ruddox, An Chau Maria Le, Bjørn Bendz, John Munkhaugen, Ole Klungsøyr, Thor Edvardsen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jan Erik OtterstadDepartment of Cardiology, Vestfold Hospital Trust, Tønsberg, Norway, P. O Box 2168, 3103, Tønsberg, Norway.
Ingvild Billehaug NorumDepartment of Cardiology, Vestfold Hospital Trust, Tønsberg, Norway, P. O Box 2168, 3103, Tønsberg, Norway. innoru@siv.no.ORCID http://orcid.org/0000-0001-8928-1176
Vidar RuddoxDepartment of Cardiology, Vestfold Hospital Trust, Tønsberg, Norway, P. O Box 2168, 3103, Tønsberg, Norway.
An Chau Maria LeDepartment of Cardiology, Vestfold Hospital Trust, Tønsberg, Norway, P. O Box 2168, 3103, Tønsberg, Norway.
Bjørn BendzFaculty of Medicine, University of Oslo, Oslo, Norway, Blindern, P.O Box 1078, 0316, Oslo, Norway.
John MunkhaugenDepartment of Medicine, Drammen Hospital Trust, Drammen, Norway, Vestre Viken HF, P.O box 800, 3004, Drammen, Norway.
Ole KlungsøyrOslo Centre for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway, Sogn Arena 3.etg, Nydalen, P.O Box 4950, 0424, Oslo, Norway.
Thor EdvardsenFaculty of Medicine, University of Oslo, Oslo, Norway, Blindern, P.O Box 1078, 0316, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Global longitudinal strain (GLS) is a more sensitive prognostic factor than left ventricular ejection fraction (LVEF) in various cardiac diseases. Little is known about the clinical impact of GLS changes after acute myocardial infarction (AMI). The present study aimed to explore if non-improvement of GLS after 3 months was associated with higher risk of subsequent composite cardiovascular events (CCVE). Patients with AMI were consecutively included at a secondary care center in Norway between April 2016 and July 2018 within 4 days following percutaneous coronary intervention. Echocardiography was performed at baseline and after 3 months. Patients were categorized with non-improvement (0 to - 100%) or improvement (0 to 100%) in GLS relative to the baseline value. Among 214 patients with mean age 65 (± 10) years and mean LVEF 50% (± 8) at baseline, 50 (23%) had non-improvement (GLS: - 16.0% (± 3.7) to - 14.2% (± 3.6)) and 164 (77%) had improvement (GLS: - 14.0% (± 3.0) to - 16.9% (± 3.0%)). During a mean follow-up of 3.3 years (95% CI 3.2 to 3.4) 77 CCVE occurred in 52 patients. In adjusted Cox regression analyses, baseline GLS was associated with all recurrent CCVE (HR 1.1, 95% CI 1.0 to 1.2, p < 0.001) whereas non-improvement versus improvement over 3 months follow-up was not. Baseline GLS was significantly associated with the number of CCVE in revascularized AMI patients whereas non-improvement of GLS after 3 months was not. Further large-scale studies are needed before repeated GLS measurements may be recommended in clinical practice.Trial registration: Current Research information system in Norway (CRISTIN). Id: 506563.

Indexed as

Myocardial InfarctionVentricular Function, LeftAgedHumansPredictive Value of TestsPrognosisRisk FactorsStroke VolumeGlobal longitudinal strain improvement; PCI treated myocardial infarctionPrognostic impact

Identifiers

PMID34327649
PMCPMC8604850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.