ArticleThe Lancet regional health. Western Pacific2021
The impact of the rotavirus vaccine on diarrhoea, five years following national introduction in Fiji.
Article in The Lancet regional health. Western Pacific, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Molecular epidemiology of rotavirus causing diarrhea among under-five children after the introduction of rotavirus vaccines, Rotavac and Rotasiil, into the national immunization program of India.Virology journal · 2026Article
- Examining wealth-related inequality in childhood vaccination in Fiji using the UNICEF Multiple Indicator Cluster Survey 2021.International health · 2026Article
- Evaluation of rotavirus, pneumococcal conjugate and human papillomavirus vaccination in four Pacific island countries: A cost-effectiveness modelling study.PLoS medicine · 2026Article
- Enteric Pathogens in children under five with diarrhoea in a rotavirus vaccinated population in Coastal Ghana, 2023.PloS one · 2026Article
- Indirect Effects of Universal Infant Rotavirus Vaccination: A Narrative Systematic Review.Vaccines · 2025Review
- Vaccination and its social and behavioural drivers in children with disability in Fiji.BMJ global health · 2025Article
- "Fear of the unknown": Health, disability, and stakeholder perspectives on the behavioral and social drivers of vaccination in children with disability in Fiji.PLOS global public health · 2025Article
- Global and regional trends in under-five diarrheal disease burden: impact of human development index and geographic disparities, 1990-2021.Gastroenterology and hepatology from bed to bench · 2025Article
- Prevalence and correlates of diarrhoea among children under five in selected coastal communities in Ghana.Journal of health, population, and nutrition · 2024Article
- Article
- Review
- Social and Environmental Determinants of Diarrheal Diseases among Children under Five Years in Epworth Township, Harare.Children (Basel, Switzerland) · 2023Article
- Genotype Diversity before and after the Introduction of a Rotavirus Vaccine into the National Immunisation Program in Fiji.Pathogens (Basel, Switzerland) · 2021Article
- Welcome evidence of vaccine impact in the Pacific.The Lancet regional health. Western Pacific · 2021Article
Corrections and comments
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Authors and funding
22 authors at 10 institutions in 5 countries.
Funding
Abstract
backgroundIn 2012, Fiji became the first independent Pacific island country to introduce rotavirus vaccine. We describe the impact of rotavirus vaccine on all-cause diarrhoea admissions in all ages, and rotavirus diarrhoea in children <5 years of age.
methodsAn observational study was conducted retrospectively on all admissions to the public tertiary hospitals in Fiji (2007-2018) and prospectively on all rotavirus-positive diarrhoea admissions in children <5 years at two hospital sites (2006-2018, and 2010-2015), along with rotavirus diarrhoea outpatient presentations at one secondary public hospital (2010-2015). The impact of rotavirus vaccine was determined using incidence rate ratios (IRR) of all-cause diarrhoea admissions and rotavirus diarrhoea, comparing the pre-vaccine and post-vaccine periods. All-cause admissions were used as a control. Multiple imputation was used to impute missing stool samples.
findingsAll-cause diarrhoea admissions declined among all age groups except among infants ≤2 months old and adults ≥55 years. For children <5 years, all-cause diarrhoea admissions declined by 39% (IRR)=0•61, 95%CI; 0•57-0•65, INTERPRETATIONS: Morbidity and mortality due to rotavirus and all-cause diarrhoea in Fiji has declined in people aged 2 months to 54 years after the introduction of the RV vaccine.
fundingSupported by WHO and the Australian Government.
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Registered trials
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