Evidence map›Paper›PMID 34327296›Full record

ArticleJCO precision oncology2021

Empowering Clinical Decision Making in Oligometastatic Colorectal Cancer: The Potential Role of Drug Screening of Patient-Derived Organoids.

Gianluca Mauri, Erika Durinikova, Alessio Amatu, Federica Tosi, Andrea Cassingena, Francesco Rizzetto, Kristi Buzo, Pamela Arcella, Maria Costanza Aquilano, Emanuela Bonoldi and 5 more

Registry-linked trialOpen access · hybridAbstract readCase Reports
In one paragraph

Article in JCO precision oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05289076 (Protocol for Evaluation of Oncological Treatment in Patients With CRLM Using Zebra Fish Avatars-may This Model Improve Resection Rates and Survival in Patients With Upfront Non-resectable Metastatic Disease?), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05289076 phase1 / phase2unknown statusnot on this mapstarted 2022, after this paper: background citation

Protocol for Evaluation of Oncological Treatment in Patients With CRLM Using Zebra Fish Avatars-may This Model Improve Resection Rates and Survival in Patients With Upfront Non-resectable Metastatic Disease?

TypeinterventionalSponsorUniversity Hospital, LinkoepingRan2022 to 2025Enrolled40ConditionsColorectal Cancer Metastatic, Tumour Metastasis, Chemotherapy Effect, Tumor GrowthArmsChemotherapy drug
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Gianluca MauriNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Erika DurinikovaCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy.
Alessio AmatuNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Federica TosiNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Andrea CassingenaNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Francesco RizzettoNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Kristi BuzoCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy.
Pamela ArcellaCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy.
Maria Costanza AquilanoNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Emanuela BonoldiNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Silvia MarsoniIFOM-FIRC Institute of Molecular Oncology, Milan, Italy.
Salvatore SienaNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Alberto BardelliCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy.
Andrea Sartore-BianchiNiguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Sabrina ArenaCandiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy.
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITCandiolo Cancer Institute · ITUniversity of Milan · ITIFOM · IT

Funding

Cancer Research UK A26825Cancer Research UK A28223
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical Decision-MakingColorectal NeoplasmsDrug Screening Assays, AntitumorHumansMaleMiddle AgedNeoplasm MetastasisOrganoidsTomography, X-Ray Computed

Identifiers

PMID34327296
PMCPMC8315302
OpenAlexW3184751888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.