Evidence map›Paper›PMID 34327244›Full record

ArticleJournal of immunology research2021

Neuroprotective Effect of Taurine against Cell Death, Glial Changes, and Neuronal Loss in the Cerebellum of Rats Exposed to Chronic-Recurrent Neuroinflammation Induced by LPS.

Samara P Silva, Adriana M Zago, Fabiano B Carvalho, Lucas Germann, Gabriela de M Colombo, Francine L Rahmeier, Jessié M Gutierres, Cristina R Reschke, Margarete D Bagatini, Charles E Assmann and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Frontiers in nutrition · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Fatty Acid-DerivedNutrients · 2022
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Samara P SilvaPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.
Adriana M ZagoPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0002-6866-946X
Fabiano B CarvalhoPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0002-7927-1342
Lucas GermannPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0002-5893-8996
Gabriela de M ColomboPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.
Francine L RahmeierPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0001-9540-5526
Jessié M GutierresPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0002-9574-4007
Cristina R ReschkeSchool of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, D02 YN77, Ireland.ORCID https://orcid.org/0000-0002-0578-548X
Margarete D BagatiniGraduate Program in Medical Sciences, Federal University of Fronteira Sul, Chapecó, SC, Brazil.ORCID https://orcid.org/0000-0001-9263-4980
Charles E AssmannPostgraduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS, Brazil.ORCID https://orcid.org/0000-0002-3524-3446
Marilda da C FernandesPathology Research Laboratory, Federal University of Health Sciences of Porto Alegre, Sarmento Leite 245, CEP 90050-170 Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0003-4234-797X
Science Foundation Ireland · IEUniversidade Federal da Fronteira Sul · BRUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study investigated the neuroprotective effect of taurine against the deleterious effects of chronic-recurrent neuroinflammation induced by LPS in the cerebellum of rats. Adult male

Indexed as

AnimalsApoptosisCaspase 3CerebellumChronic DiseaseDisease Models, AnimalHumansLipopolysaccharidesMaleMicrogliaNeuroinflammatory DiseasesNeuronsNeuroprotective AgentsRatsRats, WistarRecurrenceCasp3 protein, ratCaspase 3LipopolysaccharidesNeuroprotective AgentsTaurine

Identifiers

PMID34327244
PMCPMC8277510
OpenAlexW3180464513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.