Evidence map›Paper›PMID 34327239›Full record

ArticleBioMed research international2021

Reusable, Noninvasive, and Sensitive Fluorescence Enhanced ZnO-Nanorod-Based Microarrays for Quantitative Detection of AFP in Human Serum.

Saima Rafique, Farukh Kiyani, Sumbal Jawaid, Rubina Nasir, Mahmoosh Ahmad, Shazia Bashir, Muhammad Idress, Jan Sher Khan, Rizwan Akram

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Saima RafiqueDepartment of Physics, Air University, PAF Complex, E-9, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0002-7771-0970
Farukh KiyaniDepartment of Physics, Air University, PAF Complex, E-9, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0003-1685-2788
Sumbal JawaidDepartment of Animal Sciences, Quaid e Azam University, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0002-4831-379X
Rubina NasirDepartment of Physics, Air University, PAF Complex, E-9, Islamabad 44000, Pakistan.
Mahmoosh AhmadDepartment of Biomedical Engineering and Technology, University of Engineering and Technology, Taxila, 47080 Punjab, Pakistan.ORCID https://orcid.org/0000-0003-2446-8444
Shazia BashirDepartment of Physics and Applied Mathematics, Pakistan Institute of Engineering and Applied Sciences, Islamabad 45650, Pakistan.
Muhammad IdressDepartment of Biosciences, University of Wah, Wah Cantt, Pakistan.
Jan Sher KhanDepartment of Physics, Air University, PAF Complex, E-9, Islamabad 44000, Pakistan.ORCID https://orcid.org/0000-0003-3457-5681
Rizwan AkramDepartment of Physics, Air University, PAF Complex, E-9, Islamabad 44000, Pakistan.
Air University · PKPakistan Institute of Engineering and Applied Sciences · PKQuaid-i-Azam University · PKUniversity of Engineering and Technology Taxila · PKUniversity of Wah · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fabrication of sensitive protein microarrays such as PCR used in DNA microarray is challenging due to lack of signal amplification. The development of microarrays is utilized to improve the sensitivity and limitations of detection towards primal cancer detection. The sensitivity is enhanced by the use of ZnO-nanorods and is investigated as a substrate which enhance the florescent signal to diagnose the hepatocellular carcinoma (HCC) at early stages. The substrate for deposition of ZnO-nanorods is prepared by the conventional chemical bath deposition method. The resultant highly dense ZnO-nanorods enhance the fluorescent signal 7.2 times as compared to the substrate without ZnO-nanorods. The microarray showed sensitivity of 1504.7 ng ml

Indexed as

Microarray Analysisalpha-FetoproteinsFluorescenceHumansImmunoassayLimit of DetectionNanotubesReproducibility of ResultsSerumSpectrometry, X-Ray EmissionSurface PropertiesTime FactorsX-Ray DiffractionZinc Oxidealpha-FetoproteinsZinc Oxide

Identifiers

PMID34327239
PMCPMC8302379
OpenAlexW3185754184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.