Evidence map›Paper›PMID 34326954›Full record

ReviewWorld journal of diabetes2021

Comprehensive overview of human serum albumin glycation in diabetes mellitus.

Hong-Yan Qiu, Ning-Ning Hou, Jun-Feng Shi, Yong-Ping Liu, Cheng-Xia Kan, Fang Han, Xiao-Dong Sun

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Albumin Is an Integrative Protein of Blood Plasma and Beyond.International journal of molecular sciences · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hong-Yan QiuDepartment of Endocrinology, The Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China.
Ning-Ning HouDepartment of Endocrinology, The Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China.
Jun-Feng ShiDepartment of Endocrinology, The Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China.
Yong-Ping LiuDepartment of Endocrinology, The Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China.
Cheng-Xia KanDepartment of Endocrinology, The Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China.
Fang HanDepartment of Pathology, The Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China.
Xiao-Dong SunDepartment of Endocrinology, The Affiliated Hospital of Weifang Medical University, Weifang 261031, Shandong Province, China. sxdfriend@sina.com.
Weifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of excess glucose in blood is regarded as a sweet hurt for patients with diabetes. Human serum albumin (HSA) is the most abundant protein in human plasma, which undergoes severe non-enzymatic glycation with glucose in patients with diabetes; this modifies the structure and function of HSA. Furthermore, the advanced glycation end products produced by glycated HSA can cause pathological damage to the human body through various signaling pathways, eventually leading to complications of diabetes. Many potential glycation sites on HSA have different degrees of sensitivity to glucose concentration. This review provides a comprehensive assessment of the

Indexed as

Advanced glycation end productsDiabetes mellitusDiabetic complicationsGlycation sitesHuman serum albuminNon-enzymatic glycation

Identifiers

PMID34326954
PMCPMC8311477
OpenAlexW3180026125

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.