ArticleAmerican economic journal. Economic policy2018
Supply-Side Drug Policy in the Presence of Substitutes: Evidence from the Introduction of Abuse-Deterrent Opioids.
Article in American economic journal. Economic policy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it.
- CDC Guideline For Opioid Prescribing Associated With Reduced Dispensing To Certain Patients With Chronic Pain.Health affairs (Project Hope) · 2021Guideline
- Multisystemic Therapy - Building Stronger Families (MST-BSF): Substance misuse, child neglect, and parenting outcomes from an 18-month randomized effectiveness trial.Child abuse & neglect · 2021Trial
- Applied behavioral and decision sciences in support of US FDA's drug regulatory mission.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- OxyContin reformulation and drug-related-arrest rates, property-related crimes, child maltreatment and food pantry participation.Frontiers in pharmacology · 2026Article
- Insurance coverage and provision of opioid disorder treatment: Evidence from Medicare.Journal of policy analysis and management : [the journal of the Association for Public Policy Analysis and Management] · 2026Article
- From addiction to aggression: The spillover effects of opioid policies on intimate partner violence.Journal of health economics · 2025Article
- Regulating quasi-legal markets: Evidence from pain management clinic laws.Journal of public economics · 2025Article
- What Drives Risky Prescription Opioid Use?: Evidence from Migration.The quarterly journal of economics · 2025Article
- Improving Policy Evaluations Of The Opioid Crisis.Health affairs (Project Hope) · 2025Article
- Changing Trends in Nonmedical Gabapentin Use Among a Cohort of Rural Appalachian People Who Use Drugs: A Longitudinal Study Over the Time Period of Scheduling Changes in Kentucky.The International journal on drug policy · 2025Article
- Geography And Fentanyl: Explaining The Disproportionate Rise In Opioid Overdose Deaths Among Black Americans.Health affairs (Project Hope) · 2025Article
- Prescription opioid supply-restricting policies and hospital use by people prescribed opioid medications, Victoria, 2018-22: a controlled interrupted time series analysis.The Medical journal of Australia · 2025Article
- Estimates of Illicit Opioid Use in the US.JAMA health forum · 2025Article
- Widening Racial Disparities in the U.S. Overdose Epidemic.American journal of preventive medicine · 2025Article
- Abuse-deterrent formulations and opioid-related harms in North Carolina, 2010-2018.American journal of epidemiology · 2025Article
- Rates of Receiving Medication for Opioid Use Disorder and Opioid Overdose Deaths During the Early Synthetic Opioid Crisis: A County-level Analysis.Epidemiology (Cambridge, Mass.) · 2025Article
- The Growth of Illicit Drug Use and Its Effects on Murder Rates.Health economics · 2025Article
- The association of state policies and opioid analgesic amount dispensed from retail pharmacies.Drug and alcohol dependence · 2025Article
- Understanding the demographics of the opioid overdose death crisis.Journal of population economics · 2025Article
- Fighting abuse with prescription tracking: mandatory drug monitoring and intimate partner violence.Journal of population economics · 2025Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Overdose deaths from prescription opioid pain relievers nearly quadrupled between 1999 and 2010. We study the consequences of one of the largest supply disruptions to date to abusable opioids - the introduction of an abuse-deterrent version of OxyContin in 2010. Supply-side interventions which limit access to opioids may have the unintended consequence of increasing use of substitute drugs, including heroin. Exploiting cross-state variation in OxyContin exposure, we find that states with the highest initial rates of OxyContin misuse experienced the largest increases in heroin deaths. Our results imply that the recent heroin epidemic is largely due to the reformulation of OxyContin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.