Evidence map›Paper›PMID 34326919›Full record

ArticleOxidative medicine and cellular longevity2021

Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1

Ying Bai, Jiacheng Zuo, Xin Fang, Rufeng Ma, Tian Tian, Fangfang Mo, Qianqian Mu, Yi Zhang, Na Yu, Xueli Bao and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ying BaiCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-7569-0099
Jiacheng ZuoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Xin FangBeijing University of Chinese Medicine Affiliated Third Hospital, Beijing, China.
Rufeng MaCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Tian TianCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Fangfang MoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Qianqian MuDongzhimen Hospital of Beijing University of Chinese Medicine, Beijing, China.
Yi ZhangSchool of City Management, Beijing Open University, Beijing, China.
Na YuEducational Office, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xueli BaoBeijing University of Chinese Medicine Affiliated Third Hospital, Beijing, China.
Dongwei ZhangCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Sihua GaoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-0332-3767
Dandan ZhaoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-0757-984X
Beijing University of Chinese Medicine · CNBeijing Open University · CNCapital Medical University · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Jiang Tang Xiao Ke (JTXK) granule is a classic Chinese herbal formula that has been put into clinical use in the treatment of type 2 diabetes mellitus for decades. However, whether its ability to ameliorate skeletal muscle insulin resistance (IR) is through modulation of the AMPK/SIRT1/PGC-1

Indexed as

AMP-Activated Protein KinasesAnimalsDiabetes Mellitus, ExperimentalDiet, High-FatDrugs, Chinese HerbalInsulin ResistanceMaleMiceMuscle, SkeletalSignal TransductionAMP-Activated Protein KinasesDrugs, Chinese Herbaljiang tang xiao ke

Identifiers

PMID34326919
PMCPMC8277912
OpenAlexW3181617958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.