Evidence map›Paper›PMID 34326896›Full record

ArticleStrategies in trauma and limb reconstruction

Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? An Experimental Porcine Model.

Ahmed A Abood, Ole Rahbek, Morten L Olesen, Bjørn B Christensen, Bjarne Møller-Madsen, Søren Kold

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Article in Strategies in trauma and limb reconstruction. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ahmed A AboodDepartment of Orthopaedics and Reconstruction, Aalborg University Hospital, Aalborg, Denmark.
Ole RahbekDepartment of Orthopaedics and Reconstruction, Aalborg University Hospital, Aalborg, Denmark.
Morten L OlesenDepartment of Orthopaedics and Reconstruction, Aarhus University Hospital, Aarhus, Denmark.
Bjørn B ChristensenDepartment of Orthopaedics and Reconstruction, Aarhus University Hospital, Aarhus, Denmark.
Bjarne Møller-MadsenDepartment of Orthopaedics and Reconstruction, Aarhus University Hospital, Aarhus, Denmark.
Søren KoldDepartment of Orthopaedics and Reconstruction, Aalborg University Hospital, Aalborg, Denmark.
Aalborg University Hospital · DKAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MATERIALS AND

methodsThe study was carried out using an experimental porcine model. Eleven juvenile female porcines were randomized for insertion of a retrograde femoral nail in one limb. The other limb acted as a control. The animals were housed for 8 weeks before the nail was removed and housed for 8 additional weeks, that is, 16 weeks in total. Growth was assessed by interphyseal distance on 3D magnetic resonance imaging (MRI) after 16 weeks and the operated limb was compared to the non-operated limb. Histomorphometric analysis of the physeal canal was performed.

resultsNo difference in longitudinal growth was observed when comparing the operated femur to the non-operated femur using MRI after 16 weeks. No osseous tissue crossing the physis was observed on MRI or histology. The empty canal in the physis after nail removal was filled with fibrous tissue 16 weeks after primary surgery.

conclusionGrowth was not impaired and no bone bridges were seen on MRI or histology 16 weeks after insertion and later removal of the retrograde femoral nail. CLINICAL SIGNIFICANCE: The insertion of a retrograde intramedullary femoral nail centrally through the physis and later removal might be safe, however, long-term follow-up is needed. AIM AND

objectiveThe insertion of an intramedullary nail may be beneficial in certain cases of leg length discrepancy (LLD) in children. However, it is unknown if the physeal injury due to the surgery may cause bone bridge formation and thereby growth arrest after removal. This study aimed to assess longitudinal interphyseal growth 16 weeks after insertion and later removal of a retrograde femoral nail passing through the physis. Moreover, to analyse the tissue forming in the empty physeal canal after removal of the nail. HOW TO CITE THIS ARTICLE: Abood AA, Rahbek O, Olesen ML,

Indexed as

ChildrenIntramedullary nailLeg length discrepancy

Identifiers

PMID34326896
PMCPMC8311745
OpenAlexW3186873039

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.