Evidence map›Paper›PMID 34326814›Full record

Observational studyFrontiers in endocrinology2021

The Effect of Lockdown and Physical Activity on Glycemic Control in Italian Children and Young Patients With Type 1 Diabetes.

Nicola Minuto, Marta Bassi, Carolina Montobbio, Francesco Vinci, Claudia Mercuri, Francesca Nastasia Perri, Mara Cabri, Maria Grazia Calevo, Giuseppe d'Annunzio, Mohamad Maghnie

Abstract readObservational Study
In one paragraph

Observational study in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Endocrine manifestations of COVID-19 in children: A scoping review.Best practice & research. Clinical endocrinology & metabolism · 2023
    Article
  8. Review
  9. Physical Activity in the COVID-19 Era and Its Impact on Adolescents' Well-Being.International journal of environmental research and public health · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicola MinutoDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Marta BassiDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy.
Carolina MontobbioDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy.
Francesco VinciDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy.
Claudia MercuriDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy.
Francesca Nastasia PerriDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy.
Mara CabriDepartment of Neuroscience, Rehabilitation, Ophtalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy.
Maria Grazia CalevoEpidemiology and Biostatistics Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Giuseppe d'AnnunzioDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Mohamad MaghnieDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The purpose of the study was to evaluate the impact of the lockdown established by the Italian government to limit the spread of Coronavirus disease (COVID-19) on glycemic control in a large sample of patients with type 1 diabetes (T1D) based on age, type of insulin therapy, number of telemedicine visits and physical activity. Material and Methods: We retrospectively evaluated glycemic control in young T1D patients using the DexcomG6 Results: Data showed a significant improvement of TIR from 54.58% at T0 to 59.09% at T1 (p ≤0.0001). Glycemic control improved significantly in patients ≥14 years old, showing the best outcome in the "university students and young adults" group (55.40% at T0 and 61.37% at T1, p ≤0.001). All patients reduced physical activity during lockdown; in the 56 patients of "intense physical activity" group both at T0 and T1 TIR increased from ±56.91 to 64.11% (p ≤0.0001). Conclusions: Overall, the lockdown led to an unexpected improvement in glycemic control of young patients with T1D. A healthier and stressless lifestyle changes in association with the maintenance of physical activity resulted in a significant age-proportional improvement in glycemic control.

Indexed as

ExerciseAdolescentAdultChildChild, PreschoolCOVID-19Diabetes Mellitus, Type 1FemaleGlycemic ControlHumansItalyLife StyleMaleQuarantineRetrospective StudiesYoung Adultchildrencontinuous glucose monitoringCOVID-19glycemic controlphysical activitytype 1 diabetes

Identifiers

PMID34326814
PMCPMC8315148

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.