Evidence map›Paper›PMID 34326811›Full record

ArticleFrontiers in endocrinology2021

Co-Occurrence of Familial Non-Medullary Thyroid Cancer (FNMTC) and Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Associated Tumors-A Cohort Study.

Kshama Aswath, James Welch, Sriram Gubbi, Padmasree Veeraraghavan, Shirisha Avadhanula, Sudheer Kumar Gara, Esra Dikoglu, Maria Merino, Mark Raffeld, Liqiang Xi and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Kshama AswathMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
James WelchMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Sriram GubbiMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Padmasree VeeraraghavanMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Shirisha AvadhanulaDepartment of Endocrinology, Diabetes and Metabolism, Cleveland Clinic, Cleveland, OH, United States.
Sudheer Kumar GaraNational Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Esra DikogluMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Maria MerinoMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Mark RaffeldNational Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Liqiang XiNational Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Electron KebebewDepartment of Surgery, Stanford University, Stanford, CA, United States.
Joanna Klubo-GwiezdzinskaMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
National Institutes of Health · USNational Institute of Diabetes and Digestive and Kidney Diseases · USCleveland Clinic · USNational Cancer Institute · USStanford University · US

Funding

Studies of Benign and Malignant Thyroid DiseaseZIADK047053 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KLUBO-GWIEZDZINSKA, JOANNA · 2009 to 2025
$4.3M
6 · The paper itself

Abstract

Familial non-medullary thyroid cancer (FNMTC) is a form of endocrine malignancy exhibiting an autosomal dominant mode of inheritance with largely unknown germline molecular mechanism. Hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is another hereditary autosomal dominant cancer syndrome which, if proven to be caused by germline mutations in mismatch repair genes (MMR)-

Indexed as

AdolescentAdultAgedAged, 80 and overChildCohort StudiesColorectal Neoplasms, Hereditary NonpolyposisComorbidityCytological TechniquesDNA Mismatch RepairExomeFamily HealthFemaleGenetic Predisposition to DiseaseGenetic VariationGerm-Line MutationBRAF protein, humanProto-Oncogene Proteins B-rafexome sequencingfamilial non-medullary thyroid carcinomahereditary non-polyposis colorectal cancermismatch repair genesthyroid cancer

Identifiers

PMID34326811
PMCPMC8315151
OpenAlexW3179763921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.