Evidence map›Paper›PMID 34326686›Full record

ArticleInternational journal of biological sciences2021

Combination of Ferulic Acid, Ligustrazine and Tetrahydropalmatine attenuates Epithelial-mesenchymal Transformation

Chengling Zhang, Ying Zhang, Haiying Pan, Yi Tan, Qinghua Wei, Xueshan Dai, Jiahui Wei, Yi Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  9. EHMT2-mediated transcriptional reprogramming drives neuroendocrine transformation in non-small cell lung cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chengling ZhangCollege of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing, China.
Ying ZhangCollege of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing, China.
Haiying PanSichuan Jinxin Women & Children Hospital, Chengdu 610066, China.
Yi TanCollege of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing, China.
Qinghua WeiCollege of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing, China.
Xueshan DaiCollege of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing, China.
Jiahui WeiCollege of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing, China.
Yi ChenCollege of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing, China.
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously the potential therapeutic action of ferulic acid, ligustrazine and tetrahydropalmatine (FLT) are discovered with unclear mechanism in rat autograft endometriosis. However, the effect of FLT on endometrial cells and allograft endometriosis is still unclear. This study is designed to elucidate the influence of FLT on epithelial-mesenchymal transformation in allograft endometriosis and endometrium cells.

Indexed as

AnimalsBerberine Alkaloidsbeta CateninCoumaric AcidsDisease Models, AnimalDrug Therapy, CombinationEndometriosisEndometriumEpithelial-Mesenchymal TransitionEstrogensFemaleHeterograftsMiceMice, Inbred C3HMice, NudeProgesteroneBerberine Alkaloidsbeta CateninCoumaric AcidsEstrogensferulic acidProgesteronePyrazinestetrahydropalmatinetetramethylpyrazineAllograft endometriosisEpithelial-mesenchymal transformationFerulic acidLigustrazineTetrahydropalmatineWnt/β-catenin pathway

Identifiers

PMID34326686
PMCPMC8315018
OpenAlexW3173249234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.