Evidence map›Paper›PMID 34326684›Full record

ArticleInternational journal of biological sciences2021

USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.

Haiqing He, Lu Yi, Bin Zhang, Bin Yan, Ming Xiao, Jiannan Ren, Dong Zi, Liang Zhu, Zhaohui Zhong, Xiaokun Zhao and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 121 citations in OpenAlex.

  1. The gasdermin family: from pyroptosis mechanisms to therapeutic targets.Signal transduction and targeted therapy · 2026
    Review
  2. Associations ofBiomolecules · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Role of Gasdermin B-Mediated Pyroptosis in Bladder Cancer Diagnosis.International journal of molecular sciences · 2026
    Article
  8. Pyroptosis: Turning Up the Heat on Cancer.Annual review of immunology · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Mechanistic insights into gasdermin-mediated pyroptosis.Nature reviews. Molecular cell biology · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Role of gasdermins in chronic kidney disease.Frontiers in immunology · 2025
    Review

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Haiqing HeDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Lu YiDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Bin ZhangCancer center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Bin YanDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Ming XiaoDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Jiannan RenDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Dong ZiDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Liang ZhuDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Zhaohui ZhongDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Xiaokun ZhaoDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Xin JinDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Wei XiongDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorCell ProliferationGasderminsHumansImmunohistochemistryMiceMice, Inbred BALB CMice, NudePhosphorylationPore Forming Cytotoxic ProteinsRNA, MessengerSignal TransductionSTAT3 Transcription FactorUbiquitin ThiolesteraseUp-RegulationGasderminsGSDMB protein, humanPore Forming Cytotoxic ProteinsRNA, MessengerSTAT3 protein, humanSTAT3 Transcription FactorUbiquitin ThiolesteraseUSP24 protein, humanbladder cancerGSDMBSTAT3USP24

Identifiers

PMID34326684
PMCPMC8315027
OpenAlexW3175095680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.