Evidence map›Paper›PMID 34326660›Full record

ArticleInternational journal of general medicine2021

The Red Blood Cell Distribution Width-Albumin Ratio: A Promising Predictor of Mortality in Stroke Patients.

Na Zhao, WanHua Hu, Zhimin Wu, Xujie Wu, Wei Li, Yiru Wang, Han Zhao

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.

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  16. Prognostic value of the red cell distribution width to albumin ratio in predicting mortality in elderly hip fracture patients undergoing hemiarthroplasty.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Na ZhaoDepartment of Neurology, Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang, Wenzhou, 325000, People's Republic of China.
WanHua HuDepartment of Neurology, Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang, Wenzhou, 325000, People's Republic of China.
Zhimin WuDepartment of Neurology, Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang, Wenzhou, 325000, People's Republic of China.
Xujie WuDepartment of Neurology, Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang, Wenzhou, 325000, People's Republic of China.
Wei LiDepartment of Neurology, Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang, Wenzhou, 325000, People's Republic of China.
Yiru WangDepartment of Neurology, Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang, Wenzhou, 325000, People's Republic of China.
Han ZhaoDepartment of Neurology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Zhejiang, Wenzhou, 325000, People's Republic of China.
Wenzhou Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWithin this study we attempt to express a correlation between the mortality of stroke and stroke related infection to a novel biomarker represented by the red blood cell width-albumin levels ratio within the patient. We hypothesize that this novel biomarker could be utilized as better predictive tool for stroke associated infections.

methodsPatient data sets were obtained via the Medical Information Mart for Intensive Care Database iii V1.4 (MIMIC-iii). Data from 1480 patients were obtained to serve the testing for the RA biomarker tests. Clinical endpoints of 30-, 60-, and 365-day all-cause mortality in stroke patients were used as subgroups within the analyzed population. Estimation of hazard ratios (HR) were obtained from Cox regression models for stroke-associated infection and all-cause mortality in relation to RA values.

resultsA high-RA was associated with increased mortality in ICU patients suffering from a stroke. After adjusting for age and sex, compared to the reference group (the first quartile), the high-RA group had the highest 30-day (HR, 95% CI: 1.88 (1.36, 2.58)), 90-day (HR, 95% CI: 2.12 (1.59, 2.82)), and one-year (HR, 95% CI: 2.15 (1.65, 2.80)) all-cause mortality. The RA values were independently associated with an increased risk of stroke-associated infection when adjusting for confounders.

conclusionsOur data suggest RA may be an easily accessible, reproducible, and low-cost biomarker for predicting stroke-associated infections and mortality in patients who have suffered from a stroke.

Indexed as

all-cause mortalityred blood cell distribution width–albumin ratiostrokestroke-associated infection

Identifiers

PMID34326660
PMCPMC8315287
OpenAlexW3183266587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.