ReviewWorld journal of gastroenterology2021
Prevention of vertical transmission of hepatitis B virus infection.
Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Global epidemiology of hepatitis B virus infection in dialysis patients: a systematic review and meta-analysis of prevalence, immunity, risk factors, and beyond.International urology and nephrology · 2026Pooled it
- Vertical Transmission of Hepatitis B and C-Then and Now-A Comprehensive Literature Systematic Review.Viruses · 2025Pooled it
- Comprehensive Interventions in HBV Care: Nursing-Sensitive Approach.Gynecologic and obstetric investigation · 2025Trial
- Immunogenicity of a Birth Dose of Hepatitis B Vaccine in Kinshasa, Democratic Republic of Congo: A Randomised, Controlled Trial.Journal of viral hepatitis · 2024Trial
- Oxidative stress in neurodegeneration: from a simple insult to a dynamic regulator.Redox report : communications in free radical research · 2026Review
- High screening coverage and positivity rates of HIV, syphilis, and hepatitis B among pregnant women accessing antenatal care in Sierra Leone.Public health action · 2026Article
- RRM2B is associated with low-level viremia during entecavir therapy in pediatric chronic hepatitis B and promotes profibrotic signaling in vitro.Virology journal · 2026Article
- Knowledge and Attitudes of Women in the Pre- and Postnatal Period on Screening and Mother-to-Child Transmission of the Hepatitis B Virus in Mali.Journal of community health · 2026Article
- Vertical transmission of Orf virus in goats and its prevention.Veterinary research · 2026Article
- The effects of spatial structure on a host-parasite model with horizontal and vertical transmission.Theoretical ecology · 2026Article
- Interferon therapy for chronic hepatitis B in children: an immunological perspective.Frontiers in immunology · 2026Review
- Knowledge, perceptions, and health education needs regarding hepatitis B virus among HBsAg-positive pregnant women in Taiyuan, China: a cross-sectional study.BMC public health · 2025Article
- Epidemiology of hepatitis B and C viruses among pregnant women at Queen Elizabeth Central Hospital (QECH), Blantyre Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2025Article
- Prevalence and Diagnostic Determinants of Hepatitis B Infection Among Saudi Adults: Implications for Targeted Screening and Early Detection.Diagnostics (Basel, Switzerland) · 2025Article
- [Hepatitis diagnostics : Differential diagnosis of viral hepatitis from other causes of elevated transaminases].Pathologie (Heidelberg, Germany) · 2025Review
- Real-World Study for Mother-To-Child Transmission of Hepatitis B in Guangdong Province, 2021-2023.Journal of viral hepatitis · 2025Article
- Pathogenesis, prevention, and therapeutic advances in hepatitis B, C, and D.Virology journal · 2025Review
- Hepatitis B serosurvey to validate the achievement of regional hepatitis B control targets in Belarus.Vaccine · 2025Article
- Vaccination Status and Influencing Factors of Delayed Vaccination in Toddlers Born to Hepatitis B Surface Antigen-Positive Mothers.Vaccines · 2025Article
- Hepatitis B virus impacts embryonic development and methylation of maternal genes in assisted reproductive technology patients.Journal of assisted reproduction and genetics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis B virus (HBV) is the leading cause of chronic viral hepatitis. Annually, almost two million children younger than 5 years acquire the infection, mostly through vertical or horizontal transmission in early life. Vertical transmission of HBV is a high efficacy phenomenon ranging, in the absence of any preventive interventions, from 70% to 90% for hepatitis e antigen positive mothers and from 10% to 40% for hepatitis e antigen-negative mothers. Maternal viraemia is a preeminent risk factor for vertical transmission of HBV. Maternal screening is the first step to prevent vertical transmission of HBV. Hepatitis B passive and active immunoprophylaxis at birth together with antiviral treatment of highly viraemic mothers are the key strategies for global elimination of HBV infection. Strategies are needed to promote implementation of birth-dose vaccination and hepatitis B immunoglobulins in low- and middle-income countries where the prevalence of the infection is at the highest.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.