ReviewWorld journal of gastroenterology2021
Acute kidney injury and hepatorenal syndrome in cirrhosis.
Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 69 citations in OpenAlex.
- Urinary neutrophil gelatinase-associated lipocalin: a key biomarker for differentiating acute kidney injury and predicting short-term mortality in liver cirrhosis patients.Renal failure · 2026Observational
- Determinants of Acute Kidney Injury After Endoscopic Retrograde Cholangiopancreatography in Patients With Liver Cirrhosis: Retrospective Observational Study.JMIR medical informatics · 2026Observational
- Association of Early Albumin Administration with Clinical Outcomes in Patients Hospitalized with Spontaneous Bacterial Peritonitis: A Propensity-Matched Cohort Study.Reports (MDPI) · 2026Article
- Cytokine storm in acute respiratory distress syndrome.Journal of intensive medicine · 2026Review
- Risk of Severe Acute Kidney Injury According to the Presence of Nephrotic-Range Proteinuria in Patients with Liver Cirrhosis: A Retrospective Cohort Study (2016-2025).Medicina (Kaunas, Lithuania) · 2026Article
- Observational
- Nonintensive Care Unit Norepinephrine as an Alternative to Terlipressin in Hepatorenal Syndrome-Acute Kidney Injury.Gastro hep advances · 2026Article
- Exploring the Therapeutic Role of Pregnane X Receptor Activation in Acute Kidney Injury: Mechanisms and Clinical Implications.Current molecular medicine · 2026Review
- Creatinine-to-albumin ratio and all-cause mortality in patients with upper gastrointestinal bleeding: a retrospective study.BMC gastroenterology · 2025Article
- Evaluation of Prognosis in Cirrhotic Patients with Esophageal Variceal Bleeding Using Non-Invasive Scores.Medicina (Kaunas, Lithuania) · 2025Article
- Association between the C-reactive protein-triglyceride-glucose index (CTI) and the risk of acute kidney injury in critically ill patients with cirrhosis.BMC nephrology · 2025Article
- The association between potassium level during the anhepatic stage of orthotopic liver transplantation and postoperative acute kidney injury: an exploratory study.BMC nephrology · 2025Observational
- Correlation of Serum Zinc Levels with Hepatic Encephalopathy Severity in Patients with Decompensated Liver Cirrhosis: A Prospective Observational Study from Egypt.Biological trace element research · 2025Observational
- Acute Kidney Injury in Patients with Liver Cirrhosis: From Past to Present Definition and Diagnosis.Life (Basel, Switzerland) · 2025Review
- Association between standard base excess and acute kidney injury in intensive care unit patients: a study based on the medical information mart for intensive care database.BMC nephrology · 2025Article
- Role of sonographic hepatorenal index and renal resistive index in monitoring of acute kidney injury after liver transplantation.World journal of radiology · 2025Article
- Harnessing the power of nanoagents in acute kidney injury: A versatile platform for imaging and treatment.Coordination chemistry reviews · 2025Article
- Outcomes of Acute Pancreatitis in Patients With and Without Liver Cirrhosis: A Retrospective Analysis.Cureus · 2025Article
- Article
- Construction of a prediction model for hepatic encephalopathy in acute-on-chronic liver failure patients.Annals of medicine · 2024Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) in cirrhosis, including hepatorenal syndrome (HRS), is a common and serious complication in cirrhotic patients, leading to significant morbidity and mortality. AKI is separated into two categories, non-HRS AKI and HRS-AKI. The most recent definition and diagnostic criteria of AKI in cirrhosis and HRS have helped diagnose and prognosticate the disease. The pathophysiology behind non-HRS-AKI and HRS is more complicated than once theorized and involves more processes than just splanchnic vasodilation. The common biomarkers clinicians use to assess kidney injury have significant limitations in cirrhosis patients; novel biomarkers being studied have shown promise but require further studies in clinical settings and animal models. The overall management of non-HRS AKI and HRS-AKI requires a systematic approach. Although pharmacological treatments have shown mortality benefit, the ideal HRS treatment option is liver transplantation with or without simultaneous kidney transplantation. Further research is required to optimize pharmacologic and nonpharmacologic approaches to treatment. This article reviews the current guidelines and recommendations of AKI in cirrhosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.