Evidence map›Paper›PMID 34326478›Full record

ArticleMucosal immunology2021

Effector memory CD4

Aiko Ono-Ohmachi, Satoki Yamada, Satoru Uno, Masato Tamai, Kohei Soga, Shotaro Nakamura, Nobuyuki Udagawa, Yuko Nakamichi, Masanori Koide, Yoshikazu Morita and 10 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. A pathological joint-liver axis mediated by matrikine-activated CD4Signal transduction and targeted therapy · 2024
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 2 countries.

Aiko Ono-OhmachiMilk Science Research Institute, Megmilk Snow Brand Co., Ltd., Saitama, Japan.
Satoki YamadaResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Satoru UnoResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Masato TamaiResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Kohei SogaResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Shotaro NakamuraResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Nobuyuki UdagawaDepartment of Biochemistry, Matsumoto Dental University, Nagano, Japan.
Yuko NakamichiInstitute for Oral Science, Matsumoto Dental University, Nagano, Japan.
Masanori KoideInstitute for Oral Science, Matsumoto Dental University, Nagano, Japan.
Yoshikazu MoritaMilk Science Research Institute, Megmilk Snow Brand Co., Ltd., Saitama, Japan.
Tomohiro TakanoResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Takumi ItohDepartment of Therapy Development and Innovation for Immune Disorders and Cancers, Juntendo University, Tokyo, Japan.
Shigeru KakutaLaboratory of Biomedical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Chikao MorimotoDepartment of Therapy Development and Innovation for Immune Disorders and Cancers, Juntendo University, Tokyo, Japan.
Shuji MatsuokaDepartment of Immunological Diagnosis, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Yoichiro IwakuraResearch Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
Michio TomuraLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Nishikiorikita, Tondabayashi-shi, Osaka, Japan.
Hiroshi KiyonoIMSUT Distinguished Professor Unit, Division of Mucosal Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Satoshi HachimuraResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Haruyo Nakajima-AdachiResearch Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan. haruyona@g.ecc.u-tokyo.ac.jp.ORCID 0000-0003-2008-2501
The University of Tokyo · JPJuntendo University · JPMatsumoto Dental University · JPMegmilk Snow Brand (Japan) · JPChiba University · JPOsaka Ohtani University · JPTokyo University of Agriculture · JPTokyo University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal inflammation can be accompanied by osteoporosis, but their relationship, mediated by immune responses, remains unclear. Here, we investigated a non-IgE-mediated food-allergic enteropathy model of ovalbumin (OVA) 23-3 mice expressing OVA-specific T-cell-receptor transgenes. Mesenteric lymph nodes (MLNs) and their pathogenic CD4

Indexed as

AnimalsBiomarkersBone ResorptionCD4-Positive T-LymphocytesCytokinesDisease Models, AnimalDisease SusceptibilityFood HypersensitivityImmunophenotypingInterleukin-4Intestinal DiseasesLymph NodesMemory T CellsMesenteryMiceModels, BiologicalBiomarkersCytokinesInterleukin-4

Identifiers

PMID34326478
OpenAlexW3185174773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.