Evidence map›Paper›PMID 34326462›Full record

Observational studySpinal cord2022

Reliability and validity of the international standards for neurological classification of spinal cord injury in patients with non-traumatic spinal cord lesions.

Emanuela Lena, Ilaria Baroncini, Chiara Pavese, Gaia Musumeci, Silvia Volini, Marcella Masciullo, Beatrice Aiachini, Gabriella Fizzotti, Mariangela V Puci, Giorgio Scivoletto

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Spinal cord, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Gait analysis methods in people with spinal cord injury: a systematic review.Journal of neuroengineering and rehabilitation · 2026
    Pooled it
  2. Pooled it
  3. ShuffleLeNet architecture for spinal cord injury classification and level detection.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  15. Prediction of bowel management independence after ischemic spinal cord injury.European journal of physical and rehabilitation medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emanuela LenaINI Rehabilitation Hospital, Grottaferrata, Italy.
Ilaria BaronciniMontecatone Rehabilitation Hospital, Imola, Italy.
Chiara PaveseDepartment of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.ORCID http://orcid.org/0000-0002-2061-0346
Gaia MusumeciMontecatone Rehabilitation Hospital, Imola, Italy.
Silvia VoliniMontecatone Rehabilitation Hospital, Imola, Italy.
Marcella MasciulloSpinal Cord Unit, IRCCS Fondazione Santa Lucia, Rome, Italy.
Beatrice AiachiniNeurorehabilitation and Spinal Unit, Institute of Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Gabriella FizzottiNeurorehabilitation and Spinal Unit, Institute of Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Mariangela V PuciUnit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Giorgio ScivolettoSpinal Cord Unit, IRCCS Fondazione Santa Lucia, Rome, Italy. g.scivoletto@hsantalucia.it.ORCID http://orcid.org/0000-0001-5766-6952

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designProspective, observational study.

objectivesThe International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) represent the gold standard for the assessment of patients with spinal cord injury (SCI) and their measurement properties have been evaluated in patients with traumatic lesions. Albeit the ISNCSCI are widely used also for the assessment and prognosis of patients with non-traumatic SCI, a validation of this grading system in this sample has never been performed. Therefore, the aim of this study is to evaluate the measurement properties of the ISNCSCI in a population of persons with non-traumatic SCI.

settingThree Italian rehabilitation hospitals.

methodsThe sample included 140 patients with non-traumatic SCI of different etiology, level and grade, for a total of 169 evaluations performed by two examiners. Cronbach's Alpha was used to evaluate the internal consistency of the ISNCSCI various components. The agreement between two examiners of each center in the definition of different components was used to assess the inter-rater reliability. The construct validity was evaluated through the correlation of the ISNCSCI with the Spinal Cord Independence Measure (SCIM).

resultsThe ISNCSCI showed substantial internal consistency, and substantial inter-rater agreement for AIS grade, cumulative motor and sensory scores. The motor scores for upper and lower extremity showed fair to moderate correlation with SCIM self-care and motility subscores, respectively. The ISNCSCI total motor score correlated with the total SCIM score.

conclusionsOur study demonstrates that the ISNCSCI are a valid and reliable tool for the assessment of patients with non-traumatic SCI.

Indexed as

Spinal Cord InjuriesHumansProspective StudiesReproducibility of Results

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.