ArticleScientific reports2021
Impact on patients with oral squamous cell carcinoma in different anatomical subsites: a single-center study in Taiwan.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Systematic review and standardized comparison of health-related quality-of-life instruments available for patients with oral cavity cancer and oropharyngeal cancer.BMC oral health · 2025Pooled it
- Machine learning in point-of-care automated classification of oral potentially malignant and malignant disorders: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Smart Theranostic Nanoplatforms in Oral Squamous Cell Carcinoma: Integrating Diagnosis, Targeted Therapy and Synergistic Photothermal/Photodynamic Approaches.International journal of molecular sciences · 2026Review
- Article
- Differential diagnosis between oral squamous cell carcinoma and osteomyelitis through mandibular canal changes on panoramic radiographs.BMC oral health · 2026Article
- Unraveling the relationship among lifestyle, tumor eruption site, histopathological grading, and oral squamous cell carcinoma: A clinicopathological study.Pakistan journal of medical sciences · 2026Article
- Structural equation modeling of multidimensional determinants of postoperative quality of life in patients with oral cancer.Health and quality of life outcomes · 2026Article
- Integrated analysis identifies CCNA2 as a candidate diagnostic and prognostic biomarker in oral tongue squamous cell carcinoma.Journal of applied oral science : revista FOB · 2026Article
- Variation of Gene Expression and Methylation Profiling in Gingival and Tongue Cancers.Cancer science · 2025Article
- Evolution of oral and oropharyngeal cancer in the Basque Country (Spain) from 1986-1994 to 2012-2017.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Neck dissection in pT1 maxillary squamous cell carcinoma: Necessity or overtreatment?Oral and maxillofacial surgery · 2025Article
- Demographic and Clinicopathologic Characteristics of 3723 Patients with Primary Oral Squamous Cell Carcinoma: A Consecutive, Single-Center Study Over 11 Years (2012-2023).Annals of surgical oncology · 2025Article
- Precision therapy targeting CAMK2 to overcome resistance to EGFR inhibitors in FAT1 -mutated oral squamous cell carcinoma.Chinese medical journal · 2025Article
- Prognostic Relationship Between Human Papillomavirus Status and Overall Survival in Patients with Tongue Cancer.Viruses · 2025Article
- The significance of the depth of invasion and tumor size in resected pathologic T4a gingivobuccal squamous cell carcinoma.Scientific reports · 2025Article
- Determinants of oral cavity cancer recurrence in Pakistan: findings from a cross-sectional study using an institutional cancer registry.BMC cancer · 2025Article
- Chemokines and their receptors in oral squamous cell carcinoma: mechanisms, clinical significance, and therapeutic implications.Frontiers in immunology · 2025Review
- Comparative clinicopathological study of the main anatomic locations of oral squamous cell carcinoma.Oral diseases · 2024Article
- Imaging Biomarkers of Oral Dysplasia and Carcinoma Measured with In Vivo Endoscopic Optical Coherence Tomography.Cancers · 2024Article
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of oral cavity squamous cell carcinoma (OSCC) is particularly high in South Asia. According to the National Comprehensive Cancer Network, OSCC can arise in several subsites. We investigated survival rates and the clinical and pathological characteristics of OSCC in different anatomical subsites in the Taiwanese population. We retrospectively analyzed data for 3010 patients with OSCC treated at the Changhua Christian Hospital. Subsequently, we compared clinical and pathological features of OSCC in different subsites. Pathological T4 stage OSCCs occurred in the alveolar ridge and retromolar trigone in 56.4% and 43.7% of cases, respectively. More than 25% of patients with tongue OSCC and 23.4% of those with retromolar OSCC had lymph node metastasis. The prognosis was worst for hard palate OSCC (hazard ratio 1.848; p < 0.001) and alveolar ridge OSCC (hazard ratio 1.220; p = 0.017). Retromolar OSCC recurred most often and tongue OSCC second most often. The risk for cancer-related mortality was highest for hard palate OSCC, followed by alveolar ridge and retromolar OSCC. We found distinct differences in survival among the different subsites of OSCC. Our findings may also help prompt future investigations of OSCC in different subsites in Taiwanese patients.
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