ArticleProceedings of the National Academy of Sciences of the United States of America2021
A large-scale study of stress, emotions, and blood pressure in daily life using a digital platform.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Life satisfaction and blood pressure: A coordinated analysis of 16 cohorts.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Pooled it
- The Impact of Yoga Practices on Body Composition and Vital Signs in Children and Adolescents With Obesity: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- Physiological and autonomic responses to intermittent low-lung-volume apnoea and pain sensitivity: A randomized controlled pilot trial.Experimental physiology · 2026Trial
- Am I more stressed because I'm aware of being a woman? The impact of gender identity salience on women's cardiovascular responses to stress.British journal of health psychology · 2025Trial
- Effects of a group-based compassion microintervention compared to cognitive reappraisal training on cardiovascular, self-reported, and behavioral stress reactivity among young adults: A cluster randomized controlled trial.Applied psychology. Health and well-being · 2025Trial
- Stress reduction experiments in daily life: Scaling from the lab to the world.Journal of experimental psychology. General · 2024Trial
- Validation study on cuffless ambulatory blood pressure monitoring method using bio-impedance, impedance cardiography and electrocardiography.European journal of applied physiology · 2026Article
- Randomized Personalized Trial for Stress Management Compared to Standard of Care.Journal of personalized medicine · 2026Article
- An Integrated, Evidence-Guided Framework for Chronic Kidney Disease Self-Management: Behavioral Mechanisms, Implementation Strategies, and Real-World Application.Kidney & blood pressure research · 2026Review
- Translation and psychometric validation of the Taiwanese daily stress inventory in a young university sample.Scientific reports · 2025Article
- Stress, Anxiety, and Self-Efficacy in Hypertension: Evidence from a Romanian Case-Control Study.Diseases (Basel, Switzerland) · 2025Article
- Income and education show distinct links to health and happiness in daily life.Nature human behaviour · 2025Article
- Contextualizing cognition: Socio-environmental factors shape how momentary stress predicts memory.Social science & medicine (1982) · 2025Article
- No Detectable Effects of Chronic Stress on Moral Decision-Making Are Found: A Data Reanalysis and a Pre-Registered Replication and Extension.Behavioral sciences (Basel, Switzerland) · 2025Article
- Stanford Screenomics: An Open-source Platform for Unobtrusive Multimodal Digital Trace Data Collection from Android Smartphones.medRxiv : the preprint server for health sciences · 2025Article
- Sexual orientation and daily stress and well-being.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Article
- Medically Tailored Grocery Deliveries to Improve Food Security and Hypertension in Underserved Groups: A Student-Run Pilot Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- A review of music performance anxiety in the lens of stress models.Frontiers in psychology · 2025Review
- Identity as a resource or a demand.PloS one · 2025Article
- Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Stress is often associated with pathophysiologic responses, like blood pressure (BP) reactivity, which when experienced repeatedly may be one pathway through which stress leads to poor physical health. Previous laboratory and field studies linking stress to physiological measures are limited by small samples, narrow demographics, and artificial stress manipulations, whereas large-scale studies often do not capture measures like BP reactivity in daily life. We examined perceived stress, emotions, heart rate, and BP during daily life using a 3-wk app-based study. We confirmed the validity of a smartphone-based optic sensor to measure BP and then analyzed data from more than 330,000 daily responses from over 20,000 people. Stress was conceptualized as the ratio of situational demands relative to individual resources to cope. We found that greater demands were associated with higher BP reactivity, but critically, the ratio of demands relative to resources improved prediction of BP changes. When demands were higher and resources were lower, there was higher BP reactivity. Additionally, older adults showed greater concordance between self-reported stress and physiologic responses than younger adults. We also observed that physiologic reactivity was associated with current emotional state, and both valence and arousal mattered. For example, BP increased with high-arousal negative emotions (e.g., anger) and decreased with low-arousal positive emotions (e.g., contentment). Taken together, this work underscores the potential for expanding stress science and public health data using handheld phones to reliably and validly measure physiologic responses linked to stress, emotion, and physical health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.