ArticleProceedings of the National Academy of Sciences of the United States of America2021
The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interaction between mutation type and gene pleiotropy drives parallel evolution in the laboratory.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Pooled it
- Persistent selection on size explains micro- and macroevolutionary alignments in fly wings.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Stabilizing and directional selection shape the genetic variation of gene expression in the transcriptome of Chlamydomonas.Molecular biology and evolution · 2026Article
- Evolution of crop phenotypic spaces through domestication.The New phytologist · 2026Article
- A century of theories of balancing selection.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Quantitative-genetic analysis of directional adaptation suggests low maximum sustainable rates of change in agreement with data from field populations.Scientific reports · 2025Article
- The structure of an ancient genotype-phenotype map shaped the functional evolution of a protein family.Nature ecology & evolution · 2025Article
- Developmental lines of least resistance predict standing genetic covariation but do not constrain plasticity or rapid evolution.Proceedings. Biological sciences · 2025Article
- The structure of an ancient genotype-phenotype map shaped the functional evolution of a protein family.bioRxiv : the preprint server for biology · 2025Article
- Macroevolution along developmental lines of least resistance in fly wings.Nature ecology & evolution · 2025Article
- Detecting natural selection in trait-trait coevolution.BMC ecology and evolution · 2023Article
- Developmental bias predicts 60 million years of wing shape evolution.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study inProceedings. Biological sciences · 2023Article
- Variation in mutational (co)variances.G3 (Bethesda, Md.) · 2023Article
- The "New Synthesis".Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Causes of variability in estimates of mutational variance from mutation accumulation experiments.Genetics · 2022Article
- The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population ofProceedings of the National Academy of Sciences of the United States of America · 2021Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Genetic variance is not equal for all multivariate combinations of traits. This inequality, in which some combinations of traits have abundant genetic variation while others have very little, biases the rate and direction of multivariate phenotypic evolution. However, we still understand little about what causes genetic variance to differ among trait combinations. Here, we investigate the relative roles of mutation and selection in determining the genetic variance of multivariate phenotypes. We accumulated mutations in an outbred population of
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