Evidence map›Paper›PMID 34326198›Full record

ArticleMolecular cancer therapeutics2021

Activation of the

Alan P Lombard, Wei Lou, Cameron M Armstrong, Leandro S D'Abronzo, Shu Ning, Christopher P Evans, Allen C Gao

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Genes · 2023
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alan P LombardDepartment of Urologic Surgery, University of California Davis, California.
Wei LouDepartment of Urologic Surgery, University of California Davis, California.
Cameron M ArmstrongDepartment of Urologic Surgery, University of California Davis, California.
Leandro S D'AbronzoDepartment of Urologic Surgery, University of California Davis, California.
Shu NingDepartment of Urologic Surgery, University of California Davis, California.ORCID 0000-0002-6514-0376
Christopher P EvansDepartment of Urologic Surgery, University of California Davis, California.
Allen C GaoDepartment of Urologic Surgery, University of California Davis, California. acgao@ucdavis.edu.
University of California, Davis · USVA Northern California Health Care System · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
Targeting AR variants in advanced prostate cancerR01CA225836 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GAO, ALLEN C. · 2019 to 2023
$1.8M
(PQD-1) NF-kB activation and enzalutamide therapy in metastatic castration resistR21CA179970 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GAO, ALLEN C. · 2013 to 2014
$363k
Novel mechanisms of resistance to antiandrogen therapiesI01BX004036 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI GAO, ALLEN C. · 2018 to 2022
–
BLR&D Research Career Scientist AwardIK6BX005222 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI Allen C. Gao · 2020 to 2026
–
BLRD VA I01 BX004036BLRD VA IK6 BX005222NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA225836NCI NIH HHS R21 CA179970
6 · The paper itself

Abstract

Docetaxel and cabazitaxel-based taxane chemotherapy are critical components in the management of advanced prostate cancer. However, their efficacy is hindered due to

Indexed as

Drug Resistance, NeoplasmGene Expression Regulation, NeoplasticAntineoplastic Combined Chemotherapy ProtocolsApoptosisATP Binding Cassette Transporter, Subfamily BBiomarkers, TumorCell ProliferationDocetaxelHumansMaleProstatic Neoplasms, Castration-ResistantTaxoidsTumor Cells, CulturedABCB1 protein, humanATP Binding Cassette Transporter, Subfamily BBiomarkers, TumorcabazitaxelDocetaxelTaxoids

Identifiers

PMID34326198
PMCPMC8492550
OpenAlexW3184505376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.