ArticleAJNR. American journal of neuroradiology2021
Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement.
Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Artificial intelligence diagnostic performance in image-based vulnerable carotid plaque detection: a systematic review and meta-analysis.BMC medical informatics and decision making · 2025Pooled it
- Radiomics-based machine learning atherosclerotic carotid artery disease in ultrasound: systematic review with meta-analysis of RQS.Journal of ultrasound · 2025Pooled it
- Large language model assistance for report-based carotid plaque AHA classification: a multi-reader study.Insights into imaging · 2026Article
- A Novel Dual-Modality Dual-View Hybrid Deep Learning-Machine Learning Framework for the Prediction of Carotid Plaque Vulnerability via Late Fusion.Diagnostics (Basel, Switzerland) · 2026Article
- Association of Carotid Plaque Gray-scale Median with Plaque Size and Degree of Stenosis.Current medical imaging · 2026Article
- Deep learning-based automatic segmentation of arterial vessel walls and plaques in MR vessel wall images for quantitative assessment.European radiology · 2025Article
- Deep learning-based key point detection algorithm assisting vessel centerline extraction.Quantitative imaging in medicine and surgery · 2025Article
- Photon-Counting Computed Tomography Angiography of Carotid Arteries: A Topical Narrative Review with Case Examples.Diagnostics (Basel, Switzerland) · 2024Review
- Combined near infrared photoacoustic imaging and ultrasound detects vulnerable atherosclerotic plaque.Biomaterials · 2023Article
- Innate and Adaptive Immunity-Related Markers as Predictors of the Short-Term Progression of Subclinical Atherosclerosis in Middle-Aged Patients.International journal of molecular sciences · 2023Article
- Antithrombotic Therapy in Peripheral Artery Disease: Current Evidence and Future Directions.Journal of cardiovascular development and disease · 2023Review
- Reassessing the Carotid Artery Plaque "Rim Sign" on CTA: A New Analysis with Histopathologic Confirmation.AJNR. American journal of neuroradiology · 2022Article
- Impact Analysis of Different CT Configurations of Carotid Artery Plaque Calcifications on Cerebrovascular Events.AJNR. American journal of neuroradiology · 2022Article
- Inflammatory Cells in Atherosclerosis.Antioxidants (Basel, Switzerland) · 2022Review
- Non-HDL-C/HDL-C ratio is associated with carotid plaque stability in general population: A cross-sectional study.Frontiers in neurology · 2022Article
- Triglyceride-Glucose Index Is Related to Carotid Plaque and Its Stability in Nondiabetic Adults: A Cross-Sectional Study.Frontiers in neurology · 2022Article
- Non-stenotic Carotid Plaques in Embolic Stroke of Unknown Source.Frontiers in neurology · 2021Review
- Carotid total plaque area as an independent predictor of short-term subclinical polyvascular atherosclerosis progression and major adverse cardiac and cerebrovascular events.Therapeutic advances in cardiovascular diseaseArticle
- Observer Variability in CT Angiography Carotid Segmentation: Assessing Variability to Set Minimum Clinical Performance.Journal of neuroimaging : official journal of the American Society of NeuroimagingArticle
- Carotid plaque characteristics and their association with cardiovascular risk factors and coronary atherosclerosis in a middle-aged population.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic ResonanceArticle
Corrections and comments
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Authors and funding
33 authors at 20 institutions in 11 countries.
Funding
Abstract
Current guidelines for primary and secondary prevention of stroke in patients with carotid atherosclerosis are based on the quantification of the degree of stenosis and symptom status. Recent publications have demonstrated that plaque morphology and composition, independent of the degree of stenosis, are important in the risk stratification of carotid atherosclerotic disease. This finding raises the question as to whether current guidelines are adequate or if they should be updated with new evidence, including imaging for plaque phenotyping, risk stratification, and clinical decision-making in addition to the degree of stenosis. To further this discussion, this roadmap consensus article defines the limits of luminal imaging and highlights the current evidence supporting the role of plaque imaging. Furthermore, we identify gaps in current knowledge and suggest steps to generate high-quality evidence, to add relevant information to guidelines currently based on the quantification of stenosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.