Evidence map›Paper›PMID 34325724›Full record

ArticleBioData mining2021

GenoVault: a cloud based genomics repository.

Sankalp Jain, Amit Saxena, Suprit Hesarur, Kirti Bhadhadhara, Neeraj Bharti, Sunitha Manjari Kasibhatla, Uddhavesh Sonavane, Rajendra Joshi

Abstract read
In one paragraph

Article in BioData mining, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sankalp JainHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India.
Amit SaxenaHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India.
Suprit HesarurHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India.
Kirti BhadhadharaHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India.
Neeraj BhartiHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India.
Sunitha Manjari KasibhatlaHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India.
Uddhavesh SonavaneHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India.
Rajendra JoshiHPC-M&BA) Group, Centre for Development of Advanced Computing (C-DAC), Pune, MH, 411008, India. rajendra@cdac.in.ORCID http://orcid.org/0000-0003-1299-0091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GenoVault is a cloud-based repository for handling Next Generation Sequencing (NGS) data. It is developed using OpenStack-based private cloud with various services like keystone for authentication, cinder for block storage, neutron for networking and nova for managing compute instances for the Cloud. GenoVault uses object-based storage, which enables data to be stored as objects instead of files or blocks for faster retrieval from different distributed object nodes. Along with a web-based interface, a JavaFX-based desktop client has also been developed to meet the requirements of large file uploads that are usually seen in NGS datasets. Users can store files in their respective object-based storage areas and the metadata provided by the user during file uploads is used for querying the database. GenoVault repository is designed taking into account future needs and hence can scale both vertically and horizontally using OpenStack-based cloud features. Users have an option to make the data shareable to the public or restrict the access as private. Data security is ensured as every container is a separate entity in object-based storage architecture which is also supported by Secure File Transfer Protocol (SFTP) for data upload and download. The data is uploaded by the user in individual containers that include raw read files (fastq), processed alignment files (bam, sam, bed) and the output of variation detection (vcf). GenoVault architecture allows verification of the data in terms of integrity and authentication before making it available to collaborators as per the user's permissions. GenoVault is useful for maintaining the organization-wide NGS data generated in various labs which is not yet published and submitted to public repositories like NCBI. GenoVault also provides support to share NGS data among the collaborating institutions. GenoVault can thus manage vast volumes of NGS data on any OpenStack-based private cloud.

Indexed as

CloudGenomics repositoryNGSOpenStack

Identifiers

PMID34325724
PMCPMC8319889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.