Evidence map›Paper›PMID 34325676›Full record

Trial reportBMC cancer2021

Effects of a DVD-delivered randomized controlled physical activity intervention on functional health in cancer survivors.

Elizabeth A Salerno, Neha P Gothe, Jason Fanning, Lindsay L Peterson, Graham A Colditz, Edward McAuley

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01030419 (Activity, Gait, and Efficacy), which is not on this map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01030419 nacompletednot on this map

Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life

TypeinterventionalSponsorUniversity of Illinois at Urbana-ChampaignRan2010 to 2014Enrolled410ConditionsAgingArmsHome-based, DVD-delivered physical activity, Usual care/Wait list
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Elizabeth A SalernoDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, USA. e.salerno@wustl.edu.ORCID http://orcid.org/0000-0001-5152-3168
Neha P GotheDepartment of Kinesiology & Community Health, University of Illinois at Urbana-Champaign, Champaign, USA.
Jason FanningDepartment of Health & Exercise Science, Wake Forest School of Medicine, Winston-Salem, USA.
Lindsay L PetersonDivision of Medical Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, USA.
Graham A ColditzDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, USA.
Edward McAuleyDepartment of Kinesiology & Community Health, University of Illinois at Urbana-Champaign, Champaign, USA.
Washington University in St. Louis · USUniversity of Illinois Urbana-Champaign · USWake Forest University · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Activity Gait and Efficacy (AGE) in Order WomenR01AG020118 · NIA · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI MCAULEY, EDWARD · 2002 to 2013
$2.7M
NCI NIH HHS P30 CA091842NIA NIH HHS 2R01 AG20118NIA NIH HHS R01 AG020118
6 · The paper itself

Abstract

backgroundSupervised physical activity interventions improve functional health during cancer survivorship, but remain costly and inaccessible for many. We previously reported on the benefits of a DVD-delivered physical activity program (FlexToBa™) in older adults. This is a secondary analysis of the intervention effects among cancer survivors in the original sample.

methodsLow active, older adults who self-reported a history of cancer (N = 46; M time since diagnosis = 10.7 ± 9.4 years) participated in a 6-month, home-based physical activity intervention. Participants were randomized to either the DVD-delivered physical activity program focused on flexibility, toning, and balance (FlexToBa™; n = 22) or an attentional control condition (n = 24). Physical function was assessed by the Short Physical Performance Battery (SPPB) at baseline, end of intervention, and at 12 and 24 months after baseline.

resultsRepeated measures linear mixed models indicated a significant group*time interaction for the SPPB total score (β = - 1.14, p = 0.048), driven by improved function from baseline to six months in the FlexToBa™ group. The intervention group also had improved balance (β = - 0.56, p = 0.041) compared with controls. Similar trends emerged for the SPPB total score during follow-up; the group*time interaction from 0 to 12 months approached significance (β = - 0.97, p = 0.089) and was significant from 0 to 24 months (β = - 1.84, p = 0.012). No significant interactions emerged for other outcomes (ps > 0.11).

conclusionsA DVD-delivered physical activity intervention designed for cancer-free older adults was capable of eliciting and maintaining clinically meaningful functional improvements in a subgroup of cancer survivors, with similar effects to the original full sample. These findings inform the dissemination of evidence-based physical activity programs during survivorship.

trial registrationClinicalTrials.gov NCT01030419 . Registered 11 December 2009.

Indexed as

Cancer SurvivorsExerciseExercise TherapySurvivorshipFemaleFollow-Up StudiesHumansMaleNeoplasmsPublic Health SurveillanceCancerExercisePhysical activityPhysical functionSurvivorshipTelerehabilitation

Identifiers

PMID34325676
PMCPMC8323277
OpenAlexW3184329089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.