Evidence map›Paper›PMID 34325666›Full record

ArticleBMC gastroenterology2021

Vedolizumab combined with surgical resection successfully treated perforating Crohn's disease with peritoneal space to rectal and vaginal fistulas: a case report.

Meng-Wu Chung, Chien-Ming Chen, Jun-Te Hsu, Ren-Chin Wu, Cheng-Tang Chiu, Chia-Jung Kuo, Ming-Yao Su, Puo-Hsien Le

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meng-Wu ChungDepartment of Medical Education, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0003-1654-5892
Chien-Ming ChenDepartment of Medical Imaging and Interventions, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0001-7829-1504
Jun-Te HsuDepartment of General Surgery, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0002-7780-1792
Ren-Chin WuDepartment of Pathology, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0003-1439-0874
Cheng-Tang ChiuDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Branch, Chang Gung University College of Medicine, 5, Fu-Hsin Street, Guei-Shan District, Taoyuan City, 33305, Taiwan.ORCID http://orcid.org/0000-0002-7437-8052
Chia-Jung KuoDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Branch, Chang Gung University College of Medicine, 5, Fu-Hsin Street, Guei-Shan District, Taoyuan City, 33305, Taiwan.ORCID https://orcid.org/0000-0003-2845-6248
Ming-Yao SuTaiwan Association of the Study of Small Intestinal Disease, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0002-5229-3074
Puo-Hsien LeDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Branch, Chang Gung University College of Medicine, 5, Fu-Hsin Street, Guei-Shan District, Taoyuan City, 33305, Taiwan. puohsien@gmail.com.ORCID http://orcid.org/0000-0002-1100-5371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntestinal perforations and fistulas are common complications of Crohn's disease. However, chronic perforation with peritoneal space to rectal and vaginal fistulas have not been previously reported. CASE PRESENTATION: A 38-year-old female suffered from progressive lower abdominal pain, diarrhea and weight loss. Terminal ileal chronic perforation with intra-abdominal abscess, peritoneal space to rectal and vaginal fistulas were noted. The patient received surgical resection of the cecum and terminal ileum, and then vedolizumab treatment. Three months later, she had complete fistula closure, and her body mass index had increased from 13 to 22.

conclusionVedolizumab combined with stool diversion is effective at treating Crohn's disease with chronic perforation and complex peritoneal space to rectal and vaginal fistulas.

Indexed as

Crohn DiseaseIntestinal FistulaVaginal FistulaAdultAntibodies, Monoclonal, HumanizedFemaleHumansTreatment OutcomeAntibodies, Monoclonal, HumanizedvedolizumabCrohn’s diseaseFistulaPerforationSurgeryVedolizumab

Identifiers

PMID34325666
PMCPMC8323229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.