Evidence map›Paper›PMID 34325518›Full record

Trial reportJournal of the American Heart Association2021

Occurrence of Coronary Collaterals in Acute Myocardial Infarction and Sleep Apnea.

Verena Summerer, Michael Arzt, Henrik Fox, Olaf Oldenburg, Florian Zeman, Kurt Debl, Stefan Buchner, Stefan Stadler

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02093377 (Treatment of Sleep Apnea Early After Myocardial Infarction With Adaptive Servo-Ventilation - a Randomized Controlled Trial), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02093377 naterminatednot on this map

Treatment of Sleep Apnea Early After Myocardial Infarction With Adaptive Servo-Ventilation - a Randomized Controlled Trial

TypeinterventionalSponsorUniversity Hospital RegensburgRan2014 to 2021Enrolled79ConditionsAcute Myocardial Infarction, Sleep ApneaArmsAdaptive servo-ventilation
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Impacts of obstructive sleep apnea on collateral circulation in stroke patients with proximal middle cerebral artery stenosis or occlusion.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  5. The role of cardiac magnetic resonance imaging in obstructive sleep apnea: a systematic scoping review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  6. Clinical characteristics and outcomes of positional obstructive sleep apnea: the sleep heart health study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  7. Article
  8. Coronary Angiographic Features of de Winter Syndrome: More Than Just Occlusion of the Left Anterior Descending Artery.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Article
  9. The overlap of chronic obstructive pulmonary disease and obstructive sleep apnea in hospitalizations for acute exacerbation of chronic obstructive pulmonary disease.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Verena SummererDepartment of Internal Medicine II University Hospital Regensburg Regensburg Germany.
Michael ArztDepartment of Internal Medicine II University Hospital Regensburg Regensburg Germany.
Henrik FoxClinic for General and Interventional Cardiology/Angiology Heart and Diabetes Center NRW Ruhr University Bochum Bad Oeynhausen Germany.
Olaf OldenburgClinic for General and Interventional Cardiology/Angiology Heart and Diabetes Center NRW Ruhr University Bochum Bad Oeynhausen Germany.
Florian ZemanCenter for Clinical Studies, Biostatistics University Hospital Regensburg Regensburg Germany.
Kurt DeblDepartment of Internal Medicine II University Hospital Regensburg Regensburg Germany.
Stefan BuchnerDepartment of Internal Medicine II University Hospital Regensburg Regensburg Germany.
Stefan StadlerDepartment of Internal Medicine II University Hospital Regensburg Regensburg Germany.
University Hospital Regensburg · DEHeart and Diabetes Center North Rhine-Westphalia · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In patients with acute myocardial infarction (MI), cardioprotective effects of obstructive sleep apnea are postulated on account of hypoxemic preconditioning. The aim of this single-center substudy was to investigate a potential association between obstructive sleep apnea and the presence of coronary collaterals in patients with first-time acute MI who have been enrolled in an ongoing, multicenter clinical trial. Methods and Results In TEAM-ASV I (Treatment of Sleep Apnea Early After Myocardial Infarction With Adaptive Servo-Ventilation Trial; NCT02093377) patients with first acute MI who received a coronary angiogram within 24 hours after onset of symptoms underwent polygraphy within the first 3 days. Coronary collaterals were classified visually by assigning a Cohen-Rentrop Score (CRS) ranging between 0 (no collaterals) and 3. Of 94 analyzed patients, 14% had significant coronary collaterals with a CRS ≥2. Apnea-Hypopnea Index (AHI) score was significantly higher in patients with CRS ≥2 compared with those with CRS <2 (31/hour [11-54] versus 13/hour [4-27];

Indexed as

Myocardial InfarctionNoninvasive VentilationSleep Apnea SyndromesCollateral CirculationCoronary AngiographyCoronary CirculationCorrelation of DataFemaleHumansHypoxiaMagnetic Resonance Imaging, CineMaleMiddle AgedPolysomnographycoronary collateralshypoxic preconditioningmyocardial infarctionsleep‐disordered breathing

Identifiers

PMID34325518
PMCPMC8475663
OpenAlexW3184498637

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.