Evidence map›Paper›PMID 34325469›Full record

ArticleInternational health2022

Pre-exposure prophylaxis for transgender women and men who have sex with men: qualitative insights from healthcare providers, community organization-based leadership and end users in coastal Kenya.

Makobu Kimani, Eduard J Sanders, Oscar Chirro, Nana Mukuria, Shally Mahmoud, Tobias F Rinke de Wit, Susan M Graham, Don Operario, Elise M van der Elst

Open access · goldAbstract read
In one paragraph

Article in International health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Makobu KimaniKEMRI-Wellcome Trust Research Program, Kilifi, Kenya.ORCID 0000-0001-9275-4018
Eduard J SandersKEMRI-Wellcome Trust Research Program, Kilifi, Kenya.ORCID 0000-0002-1062-8921
Oscar ChirroKEMRI-Wellcome Trust Research Program, Kilifi, Kenya.
Nana MukuriaKEMRI-Wellcome Trust Research Program, Kilifi, Kenya.
Shally MahmoudKEMRI-Wellcome Trust Research Program, Kilifi, Kenya.
Tobias F Rinke de WitAmsterdam Institute for Global Health and Development, Department of Global Health, University of Amsterdam, Amsterdam, The Netherlands.
Susan M GrahamUniversity of Washington, Seattle, WA, USA.
Don OperarioBrown University, Providence, RI, USA.
Elise M van der ElstKEMRI-Wellcome Trust Research Program, Kilifi, Kenya.
Kenya Medical Research Institute · KEAmsterdam Institute for Global Health and Development · NLBrown University · USUniversity of Washington · US

Funding

Wellcome Trust 107752
6 · The paper itself

Abstract

Transgender women (TW) and men who have sex with men (MSM) in Kenya are disproportionately affected by human immunodeficiency virus (HIV) and would benefit substantially from pre-exposure prophylaxis (PrEP). We conducted focus group discussions (FGDs) with healthcare providers (HCPs) and TW/MSM leadership and in-depth interviews (IDIs) with PrEP-experienced MSM and TW to learn about perceived and actual barriers to PrEP programming. Eleven HCP and 10 TW/MSM leaders participated in FGDs before PrEP roll-out (January 2018) and 12 months later. Nineteen PrEP end-users (11 MSM and 8 TW) participated in IDIs. Topic guides explored PrEP knowledge, HIV acquisition risk, gender identity, motivation for PrEP uptake and adherence and PrEP-dispensing venue preferences. Braun and Clarke thematic analysis was applied. Four themes emerged: limited preparedness of HCPs to provide PrEP to TW and MSM, varied motivation for PrEP uptake and persistence among end users, lack of recognition of TW by HCPs and suggestions for PrEP programming improvement from all stakeholders. Providers' reluctance to prescribe PrEP to TW and distrust of TW towards providers calls for interventions to improve the capacity of service environments and staff HIV preventive care. Alternative locations for PrEP provision, including community-based sites, may be developed with TW/MSM leaders.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesTransgender PersonsFemaleGender IdentityHealth PersonnelHomosexuality, MaleHumansKenyaLeadershipMaleAnti-HIV AgentsKenyaMSMpre-exposure prophylaxistransgender women

Identifiers

PMID34325469
PMCPMC9070506
OpenAlexW3186007933

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.