Evidence map›Paper›PMID 34325165›Full record

ArticleJournal of affective disorders2021

Changes in severity of depression and borderline personality disorder symptoms from pregnancy to three years postpartum in adolescent mothers.

Sierra Nannini, Irene Tung, Jessie B Northrup, Stephanie D Stepp, Kate Keenan, Alison E Hipwell

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sierra NanniniDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Irene TungDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Jessie B NorthrupDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Stephanie D SteppDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.
Kate KeenanDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, USA.
Alison E HipwellDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: hipwae@upmc.edu.
University of Pittsburgh · USUniversity of Chicago · US

Funding

The Development of Conduct Disorder in GirlsR01MH056630 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOEBER, ROLF · 1998 to 2012
$18.9M
INTERDISCIPLINARY ALCOHOL RESEARCH TRAINING PROGRAMT32AA007453 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKE S.G. MOLINA · 1985 to 2026
$3.7M
Parsing the Heterogeneity of Neural Functioning in Postpartum DepressionR01HD067185 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HIPWELL, ALISON E, MOSES-KOLKO, EYDIE L · 2011 to 2015
$2.5M
Maternal Stress Resilience During Pregnancy and Offspring Emotion RegulationK01MH123505 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TUNG, IRENE · 2021 to 2025
$840k
Postpartum Psychopathology and Teenage MothersK01MH071790 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HIPWELL, ALISON E · 2005 to 2009
$731k
NIAAA NIH HHS T32 AA007453NICHD NIH HHS R01 HD067185NIMH NIH HHS K01 MH071790NIMH NIH HHS K01 MH123505NIMH NIH HHS R01 MH056630
6 · The paper itself

Abstract

backgroundThe transition to motherhood is associated with the emergence or exacerbation of symptoms of emotional distress disorders for many women. Although adolescence is a developmental period of increased risk for mood disorders and emotion dysregulation among women, little is known about changes in emotional distress across the early postpartum years among adolescent mothers. We tested the hypothesis that symptoms of depression and borderline personality disorder (BPD) would differ between pregnant and non-pregnant adolescents, and that these differences would be maintained in the three years following delivery.

methodsData were drawn from the longitudinal Pittsburgh Girls Study: 307 adolescent mothers (14-18 years) and 307 never-pregnant adolescents, matched on age, race and household receipt of public assistance, self-reported severity of depression and BPD across four years.

resultsThere were no group differences on depression severity during or after pregnancy. However, compared with their non-pregnant peers, pregnant adolescents reported more severe BPD symptoms even after comorbid depression symptoms were accounted for, and this group difference was sustained during the following three years. LIMITATIONS: Findings are based on a community sample rather than a clinical sample, which may have limited the severity of symptoms captured.

conclusionsFindings suggest that adolescent mothers are a high-risk group for BPD symptoms during and after pregnancy, highlighting pregnancy as a critical window of opportunity to reduce morbidity among young mothers and potential negative effects on the next generation.

Indexed as

Borderline Personality DisorderMothersAdolescentChild, PreschoolDepressionEmotionsFemaleHumansPostpartum PeriodPregnancyadolescent pregnancyborderline personality disorder symptomsdepressionpostpartum

Identifiers

PMID34325165
PMCPMC8410668
OpenAlexW3184770117

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.