Evidence map›Paper›PMID 34324930›Full record

Trial reportBrazilian journal of anesthesiology (Elsevier)

Analgesic effect of intercostal nerve block given preventively or at the end of operation in video-assisted thoracic surgery: a randomized clinical trial.

Weizhang Xiao, Weiwei Zhou, Xinming Chen, Jun Zhu, Qun Xue, Jiahai Shi

Registry-linked trialOpen access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06838026 (Internal, External Intercostal Nerve Block and Intercostal Catheter for Pain Management After Uniportal VATS), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06838026 nanot yet recruitingnot on this map

Internal, External Intercostal Nerve Block and Intercostal Catheter for Pain Management After Uniportal VATS: A Clinical Trial

TypeinterventionalSponsorAl-Quds UniversityRan2025 to 2026Enrolled90ConditionsThoracic, Pain, Postoperative, Analgesia, Satisfaction, PatientArmsExternal Intercostal Nerve Block, Internal Intercostal Nerve Block, Intercostal Catheter
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Anesthesiology and pain medicine.Brazilian journal of anesthesiology (Elsevier)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weizhang XiaoAffiliated Hospital of Nantong University, Department of Cardiothoracic Surgery, Nantong, China; Affiliated Hospital of Nantong University, Nantong Key Laboratory of Translational Medicine in Cardiothoracic Diseases, Nantong, China.
Weiwei ZhouAffiliated Hospital of Nantong University, Department of Anaesthesiology, Nantong, China.
Xinming ChenAffiliated Hospital of Nantong University, Department of Cardiothoracic Surgery, Nantong, China.
Jun ZhuAffiliated Hospital of Nantong University, Department of Cardiothoracic Surgery, Nantong, China.
Qun XueAffiliated Hospital of Nantong University, Department of Cardiothoracic Surgery, Nantong, China.
Jiahai ShiAffiliated Hospital of Nantong University, Department of Cardiothoracic Surgery, Nantong, China; Affiliated Hospital of Nantong University, Nantong Key Laboratory of Translational Medicine in Cardiothoracic Diseases, Nantong, China. Electronic address: happysjh167@163.com.
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the analgesic effect of intercostal nerve block (INB) with ropivacaine when given preventively or at the end of the operation in patients undergoing video-assisted thoracic surgery (VATS).

methodsA total of 50 patients undergoing VATS were randomly divided into two groups. The patients in the preventive analgesia group (PR group) were given INB with ropivacaine before the intrathoracic manipulation combined with patient-controlled analgesia (PCA). The patients in the post-procedural block group (PO group) were administered INB with ropivacaine at the end of the operation combined with PCA. To evaluate the analgesic effect, postoperative pain was assessed with the visual analogue scale (VAS) at rest and Prince Henry Pain Scale (PHPS) scale at 6, 12, 24, 48, and 72 hours after surgery.

resultsAt 6 h and 12 h post-surgery, the VAS at rest and PHPS scores in the PR group were significantly lower than those in the PO group. There were no significant differences in pain scores between two groups at 24, 48, and 72 hours post-surgery.

conclusionIn patients undergoing VATS, preventive INB with ropivacaine provided a significantly better analgesic effect in the early postoperative period (at least through 12 h post-surgery) than did INB given at the end of surgery.

Indexed as

Nerve BlockThoracic Surgery, Video-AssistedAnalgesia, Patient-ControlledAnalgesicsHumansIntercostal NervesPostoperative PainRopivacaineAnalgesicsRopivacaineAnalgesiaIntercostal nerve blockRopivacaine

Identifiers

PMID34324930
PMCPMC9515672
OpenAlexW3184639349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.