Evidence map›Paper›PMID 34324659›Full record

ArticleBlood2021

Microvesicles, but not platelets, bud off from mouse bone marrow megakaryocytes.

Joseph E Italiano, Markus Bender, Glenn Merrill-Skoloff, Cedric Ghevaert, Bernhard Nieswandt, Robert Flaumenhaft

Open access · hybridAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Joseph E ItalianoVascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Markus BenderInstitute of Experimental Biomedicine I, University Hospital, Würzburg, Germany.ORCID 0000-0002-2381-116X
Glenn Merrill-SkoloffDivision of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; and.
Cedric GhevaertWellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Department of Haematology, University of Cambridge, Cambridge, United Kingdom.
Bernhard NieswandtInstitute of Experimental Biomedicine I, University Hospital, Würzburg, Germany.ORCID 0000-0003-1454-7413
Robert FlaumenhaftDivision of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; and.
Beth Israel Deaconess Medical Center · USUniversity of Würzburg · DEBoston Children's Hospital · USWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

Cytoskeletal Mechanisms of Platelet FormationR01HL068130 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ITALIANO, JOSEPH E · 2001 to 2021
$8.1M
Thiol Isomerases in Hemostasis and ThrombosisR35HL135775 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FLAUMENHAFT, ROBERT C · 2017 to 2023
$5.5M
Medical Research Council MC_PC_17230NHLBI NIH HHS R01 HL068130NHLBI NIH HHS R35 HL135775
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBlood PlateletsBone MarrowCell-Derived MicroparticlesMegakaryocytesMice

Identifiers

PMID34324659
PMCPMC8602935
OpenAlexW3183193257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.