Evidence map›Paper›PMID 34324524›Full record

ArticlePloS one2021

Long-term effects of coronavirus disease 2019 on the cardiovascular system, CV COVID registry: A structured summary of a study protocol.

Victor Arévalos, Luis Ortega-Paz, Diego Fernandez-Rodríguez, Víctor Alfonso Jiménez-Díaz, Jordi Bañeras Rius, Gianluca Campo, Miguel Rodríguez-Santamarta, Armando Pérez de Prado, Antonio Gómez-Menchero, José Francisco Díaz Fernández and 13 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04359927 (Long-term Effects of Coronavirus 2019 Disease on the Cardiovascular System in Patients Who Have Undergone a Diagnostic Nasopharyngeal Swab for SARS-CoV-2. CV COVID-19 Registry), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04359927 unknown statusnot on this map

Long-term Effects of Coronavirus 2019 Disease on the Cardiovascular System in Patients Who Have Undergone a Diagnostic Nasopharyngeal Swab for SARS-CoV-2. CV COVID-19 Registry

Typeobservational_patient_registrySponsorHospital Clinic of BarcelonaRan2020 to 2025Enrolled4,538ConditionsSars-CoV2, Covid19, Cardiovascular Diseases, Cardiovascular Risk Factor
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Acute and Chronic Effects of COVID-19 on the Cardiovascular System.Journal of cardiovascular development and disease · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Victor ArévalosDepartment of Cardiology, Clinic Cardiovascular Institute, Hospital Universitari Clinic, Barcelona, Spain.
Luis Ortega-PazDepartment of Cardiology, Clinic Cardiovascular Institute, Hospital Universitari Clinic, Barcelona, Spain.
Diego Fernandez-RodríguezDepartment of Cardiology, Hospital Universitari Arnau de Vilanova, Lérida, Spain.ORCID 0000-0002-2793-3631
Víctor Alfonso Jiménez-DíazDepartment of Cardiology, Hospital Universitario de Vigo, Vigo, Spain.
Jordi Bañeras RiusDepartment of Cardiology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0002-7395-0862
Gianluca CampoDepartment of Cardiology, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.ORCID 0000-0002-5150-188X
Miguel Rodríguez-SantamartaDepartment of Cardiology, Hospital Universitario de León, León, Spain.ORCID 0000-0002-2244-1259
Armando Pérez de PradoDepartment of Cardiology, Hospital Universitario de León, León, Spain.
Antonio Gómez-MencheroDepartment of Cardiology, Hospital Universitario Juan Ramón Jiménez, Huelva, Spain.
José Francisco Díaz FernándezDepartment of Cardiology, Hospital Universitario Juan Ramón Jiménez, Huelva, Spain.ORCID 0000-0002-2677-0674
Claudia ScardinoDepartment of Cardiology, Hospital Universitari Joan XXIII, Tarragona, Spain.
Nieves GonzaloDepartment of Cardiology, Hospital Universitario Clínico San Carlos Madrid, Madrid, Spain.
Alberto PernigottiDepartment of Cardiology, Hospital de Tortosa Verge de la Cinta, Tarragona, Spain.
Fernando AlfonsoDepartment of Cardiology, Hospital Universitario La Princesa, Madrid, Spain.
Ignacio Jesús Amat-SantosDepartment of Cardiology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Antonio SilvestroDepartment of Cardiology, Ospedale Bolognini di Seriate, Bérgamo, Italy.
Alfonso IelasiDepartment of Cardiology, Istituto Clinico Sant'Ambrogio, Milano, Italy.
José María de la TorreDepartment of Cardiology, Hospital Marqués de Valdecilla, Santander, Spain.
Gabriela BastidasDepartment of Cardiology, Hospital Universitari Sagrat Cor, Barcelona, Spain.
Josep Gómez-LaraDepartment of Cardiology, Hospital Universitari de Bellvitge, Barcelona, Spain.
Manel SabatéDepartment of Cardiology, Clinic Cardiovascular Institute, Hospital Universitari Clinic, Barcelona, Spain.ORCID 0000-0002-2316-3705
Salvatore BrugalettaDepartment of Cardiology, Clinic Cardiovascular Institute, Hospital Universitari Clinic, Barcelona, Spain.ORCID 0000-0001-5845-1435
CV COVID-19 Registry Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients presenting with the coronavirus-2019 disease (COVID-19) may have a high risk of cardiovascular adverse events, including death from cardiovascular causes. The long-term cardiovascular outcomes of these patients are entirely unknown. We aim to perform a registry of patients who have undergone a diagnostic nasopharyngeal swab for SARS-CoV-2 and to determine their long-term cardiovascular outcomes. STUDY AND

designThis is a multicenter, observational, retrospective registry to be conducted at 17 centers in Spain and Italy (ClinicalTrials.gov number: NCT04359927). Consecutive patients older than 18 years, who underwent a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV2 in the participating institutions, will be included since March 2020, to August 2020. Patients will be classified into two groups, according to the results of the RT-PCR: COVID-19 positive or negative. The primary outcome will be cardiovascular mortality at 1 year. The secondary outcomes will be acute myocardial infarction, stroke, heart failure hospitalization, pulmonary embolism, and serious cardiac arrhythmias, at 1 year. Outcomes will be compared between the two groups. Events will be adjudicated by an independent clinical event committee.

conclusionThe results of this registry will contribute to a better understanding of the long-term cardiovascular implications of the COVID19.

Indexed as

Arrhythmias, CardiacCardiovascular SystemCOVID-19Heart FailureMyocardial InfarctionStrokeFemaleHumansItalyMaleMulticenter Studies as TopicObservational Studies as TopicPulmonary EmbolismRegistriesRetrospective StudiesSpain

Identifiers

PMID34324524
PMCPMC8320971

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.