Evidence map›Paper›PMID 34324369›Full record

ArticleThe American journal of sports medicine2021

Articular Cartilage and Meniscus Predictors of Patient-Reported Outcomes 10 Years After Anterior Cruciate Ligament Reconstruction: A Multicenter Cohort Study.

Robert H Brophy, Laura J Huston, Isaac Briskin, MOON Knee Group, Annunziato Amendola, Charles L Cox, Warren R Dunn, David C Flanigan, Morgan H Jones, Christopher C Kaeding and 9 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The American journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Robert H BrophyDepartment of Orthopaedic Surgery, Washington University School of Medicine, Chesterfield, Missouri, USA.
Laura J HustonDepartment of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Isaac BriskinCleveland Clinic Department of Quantitative Health Sciences, Cleveland, Ohio, USA.
MOON Knee GroupInvestigation performed at Washington University, Chesterfield, Missouri, USA, Vanderbilt, Nashville, Tennessee, USA, and Cleveland Clinic, Garfield Heights, Ohio, USA.
Annunziato AmendolaDepartment of Orthopaedic Surgery, Duke University, Durham, North Carolina, USA.
Charles L CoxVanderbilt University, Nashville, Tennessee, USA.
Warren R DunnFondren Orthopedic Research Institute, Houston, Texas, USA.
David C FlaniganDepartment of Orthopaedics, The Ohio State University, Columbus, Ohio, USA.
Morgan H JonesDepartment of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Christopher C KaedingDepartment of Orthopaedics, The Ohio State University, Columbus, Ohio, USA.
Robert G MarxDepartment of Orthopaedics, Hospital for Special Surgery, New York, New York, USA.
Matthew J MatavaDepartment of Orthopaedics, Washington University School of Medicine, Chesterfield, Missouri, USA.
Eric C McCartyCU Sports Medicine, Boulder, Colorado, USA.
Richard D ParkerDepartment of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Armando F VidalInvestigation performed at Washington University, Chesterfield, Missouri, USA, Vanderbilt, Nashville, Tennessee, USA, and Cleveland Clinic, Garfield Heights, Ohio, USA.
Michelle L WolcottCU Sports Medicine, Boulder, Colorado, USA.
Brian R WolfDepartment of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.
Rick W WrightDepartment of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Kurt P SpindlerDepartment of Orthopaedics, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Cleveland Clinic · USHospital for Special Surgery · USUniversity of Iowa · US

Funding

Prognosis and Predictors of ACL Reconstruction: A Multicenter Cohort StudyR01AR053684 · NIAMS · VANDERBILT UNIVERSITY · PI SPINDLER, KURT PAUL · 2006 to 2020
$8.3M
Meniscus status and activity level after ACLK23AR066133 · NIAMS · CLEVELAND CLINIC LERNER COM-CWRU · PI JONES, MORGAN HERANCOURT · 2015 to 2019
$745k
NIAMS NIH HHS K23 AR066133NIAMS NIH HHS R01 AR053684
6 · The paper itself

Abstract

backgroundArticular cartilage and meniscal damage are commonly encountered and often treated at the time of anterior cruciate ligament reconstruction (ACLR). Our understanding of how these injuries and their treatment relate to outcomes of ACLR is still evolving. HYPOTHESIS/PURPOSE: The purpose of this study was to assess whether articular cartilage and meniscal variables are predictive of 10-year outcomes after ACLR. We hypothesized that articular cartilage lesions and meniscal tears and treatment would be predictors of the International Knee Documentation Committee (IKDC), Knee injury and Osteoarthritis Outcome Score (KOOS) (all 5 subscales), and Marx activity level outcomes at 10-year follow-up after ACLR. STUDY

designCohort study (prognosis); Level of evidence, 1.

methodsBetween 2002 and 2008, individuals with ACLR were prospectively enrolled and followed longitudinally using the IKDC, KOOS, and Marx activity score completed at entry, 2, 6, and 10 years. A proportional odds logistic regression model was built incorporating variables from patient characteristics, surgical technique, articular cartilage injuries, and meniscal tears and treatment to determine the predictors (risk factors) of IKDC, KOOS, and Marx outcomes at 10 years.

resultsA total of 3273 patients were enrolled (56% male; median age, 23 years at time of enrollment). Ten-year follow-up was obtained on 79% (2575/3273) of the cohort. Incidence of concomitant pathology at the time of surgery consisted of the following: articular cartilage (medial femoral condyle [MFC], 22%; lateral femoral condyle [LFC], 15%; medial tibial plateau [MTP], 4%; lateral tibial plateau [LTP], 11%; patella, 18%; trochlea, 8%) and meniscal pathology (medial, 37%; lateral, 46%). Variables that were predictive of poorer 10-year outcomes included articular cartilage damage in the patellofemoral (

conclusionArticular cartilage injury in the patellofemoral and medial compartments at the time of ACLR and a history of medial meniscal surgery before ACLR were associated with poorer 10-year ACLR patient-reported outcomes, but meniscal injury present at the time of ACLR was not. There was limited and conflicting association of medial meniscal repair with these outcomes.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionCartilage, ArticularAdultCohort StudiesFemaleHumansMaleMenisci, TibialPatient Reported Outcome MeasuresYoung AdultACL reconstructionanterior cruciate ligamentchondral injuryIKDCKOOSMarx activitymeniscal tearoutcomes

Identifiers

PMID34324369
PMCPMC9112230
OpenAlexW3185767090

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.