Evidence map›Paper›PMID 34324303›Full record

ArticleAnalytical chemistry2021

Advanced Raman Spectroscopy Detection of Oxidative Damage in Nucleic Acid Bases: Probing Chemical Changes and Intermolecular Interactions in Guanosine at Ultralow Concentration.

Francesca Ripanti, Claudia Fasolato, Flavia Mazzarda, Simonetta Palleschi, Marina Ceccarini, Chunchun Li, Margherita Bignami, Enrico Bodo, Steven E J Bell, Filomena Mazzei and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Article
  3. Oxidative Stress and Age-Related Tumors.Antioxidants (Basel, Switzerland) · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Francesca RipantiDepartment of Physics, Sapienza University of Rome, P.le A. Moro 5, Rome, Italy.ORCID 0000-0002-9505-740X
Claudia FasolatoDepartment of Physics and Geology, University of Perugia, Via Alessandro Pascoli, Perugia, Italy.
Flavia MazzardaDepartment of Physics, Sapienza University of Rome, P.le A. Moro 5, Rome, Italy.
Simonetta PalleschiDepartment of Environment & Health, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.
Marina CeccariniNational Centre for Rare Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.
Chunchun LiSchool of Chemistry and Chemical Engineering, Queen's University of Belfast, Stranmillis Road, Belfast, Northern Ireland.
Margherita BignamiDepartment of Environment & Health, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.
Enrico BodoDepartment of Chemistry, Sapienza University of Rome, P.le A. Moro, 5, Rome, Italy.ORCID 0000-0001-8449-4711
Steven E J BellSchool of Chemistry and Chemical Engineering, Queen's University of Belfast, Stranmillis Road, Belfast, Northern Ireland.ORCID 0000-0003-3767-8985
Filomena MazzeiDepartment of Environment & Health, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.
Paolo PostorinoDepartment of Physics, Sapienza University of Rome, P.le A. Moro 5, Rome, Italy.ORCID 0000-0002-3809-0676
Istituto Superiore di Sanità · ITSapienza University of Rome · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA/RNA synthesis precursors are especially vulnerable to damage induced by reactive oxygen species occurring following oxidative stress. Guanosine triphosphates are the prevalent oxidized nucleotides, which can be misincorporated during replication, leading to mutations and cell death. Here, we present a novel method based on micro-Raman spectroscopy, combined with

Indexed as

Nucleic AcidsSpectrum Analysis, RamanGuanosineNucleotidesOxidative StressGuanosineNucleic AcidsNucleotides

Identifiers

PMID34324303
PMCPMC8382216
OpenAlexW3136666028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.