Evidence map›Paper›PMID 34324187›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Transcriptional Profiling During Neural Conversion.

Yohannes Afeworki, Hannah Wollenzien, Michael S Kareta

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yohannes AfeworkiFunctional Genomics and Bioinformatics Core, Sanford Research, Sioux Falls, SD, USA.
Hannah WollenzienDivision of Basic Biomedical Sciences, University of South Dakota, Vermillion, SD, USA.
Michael S KaretaFunctional Genomics and Bioinformatics Core, Sanford Research, Sioux Falls, SD, USA. Michael.Kareta@SanfordHealth.org.

Funding

Yeast 2 HybridP20GM103620 · NIGMS · SANFORD RESEARCH/USD · PI ROUX, KYLE J · 2013 to 2023
$24.2M
Oncogenic mechanism of Sox2 in Rb-deficient tumorsR01CA233661 · NCI · SANFORD RESEARCH/USD · PI KARETA, MICHAEL S. · 2019 to 2023
$1.9M
NCI NIH HHS R01 CA233661NIGMS NIH HHS P20 GM103620
6 · The paper itself

Abstract

The processes that underlie neuronal conversion ultimately involve a reorganization of transcriptional networks to establish a neuronal cell fate. As such, transcriptional profiling is a key component toward understanding this process. In this chapter, we will discuss methods of elucidating transcriptional networks during neuronal reprogramming and considerations that should be incorporated in experimental design.

Indexed as

Gene Expression ProfilingTranscriptomeCell DifferentiationCellular ReprogrammingGene Expression Regulation, DevelopmentalHigh-Throughput Nucleotide SequencingHumansNeuronsSequence Analysis, RNASingle-Cell AnalysisInduced neuronsNeuronal conversionRNA-seqTranscriptional profiling

Identifiers

PMID34324187
PMCPMC9131516

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.