ArticleJournal of endocrinological investigation2022
Cardiac structural and functional abnormalities in primary hyperparathyroidism.
Article in Journal of endocrinological investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Cardiovascular Alterations in Primary Hyperparathyroidism: Associations with Risk Profile, Cardiac Structure, and Function.Journal of clinical medicine · 2026Article
- Impact of Parathyroidectomy on Vascular Stiffness: Exploring Pulse Wave Velocity and Renal Resistive Index.The Journal of clinical endocrinology and metabolism · 2026Article
- Parathyroidectomy and Cardiometabolic Risks in Patients With Primary Hyperparathyroidism.JAMA network open · 2025Article
- High prevalence of hyperuricemia and its risk factors in a Chinese cohort of primary hyperparathyroidism patients.Endocrine · 2025Article
- Reversible dilated cardiomyopathy caused by primary hyperparathyroidism: A case report.World journal of cardiology · 2025Article
- Parathyroid hormone-PTH1R signaling in cardiovascular disease and homeostasis.Trends in endocrinology and metabolism: TEM · 2024Review
- Factors associated with changes in echocardiographic parameters following kidney transplantation.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Mineral and bone metabolism markers and mortality in diabetic patients on haemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Observational
- Primary Hyperparathyroidism and Cardiovascular Disease: An Association Study Using Clinical Natural Language Processing Systems and Big Data Analytics.Journal of clinical medicine · 2023Article
- Parathyroid diseases and metabolic syndrome.Journal of endocrinological investigation · 2023Review
- The preliminary study on cardiac structure and function in Chinese patients with primary hyperparathyroidism.Frontiers in endocrinology · 2023Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStudies on cardiac structural and functional abnormalities in primary hyperparathyroidism (PHPT) have yielded conflicting and inconsistent results. In this prospective case-control study, we sought to compare cardiac structure and function in symptomatic PHPT patients and controls.
methodsOne hundred consecutive symptomatic PHPT patients and 113 matched controls underwent echocardiographic evaluation by the same operator.
resultsLeft ventricular mass index (LVMI) was significantly higher in patients as compared to controls, (median of 90.95 g/m
conclusionsSymptomatic patients with PHPT have substantial cardiac structural and functional abnormalities. These abnormalities include elevated LVMI, diastolic dysfunction, and aortic valve, mitral annular, septal and myocardial calcifications. We strongly suggest and conclude that the evaluation of PHPT patients should not only include traditional end organs like bones and kidneys but also the cardiovascular system in the form of echocardiography to detect subclinical cardiac dysfunction so that the cardiovascular health of such patients can be optimized.
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