Evidence map›Paper›PMID 34324133›Full record

Observational studyIndian journal of pediatrics2022

Propensity-Matched Comparison of Very Preterm Small- and Appropriate-for-Gestational-Age Neonates.

Rajendra Prasad Anne, Venkateshwarulu Vardhelli, Tejo Pratap Oleti, Srinivas Murki, Gopireddy Murali Mohan Reddy, Saikiran Deshabhotla, Venkat Reddy Kallem, Pravin Rao Vadije

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Indian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rajendra Prasad AnneNewborn Unit, Fernandez Hospitals, Hyderabad, Telangana, 500029, India. rajendra.omc@gmail.com.ORCID http://orcid.org/0000-0002-1572-4453
Venkateshwarulu VardhelliNewborn Unit, Fernandez Hospitals, Hyderabad, Telangana, 500029, India.
Tejo Pratap OletiNewborn Unit, Fernandez Hospitals, Hyderabad, Telangana, 500029, India.
Srinivas MurkiNewborn Unit, Paramita Children's Hospital, Kothapet, L B Nagar, Hyderabad, Telangana, India.
Gopireddy Murali Mohan ReddyEvidencian Research Associates, Bengaluru, Karnataka, India.
Saikiran DeshabhotlaNewborn Unit, Fernandez Hospitals, Hyderabad, Telangana, 500029, India.
Venkat Reddy KallemNewborn Unit, Paramita Children's Hospital, Kothapet, L B Nagar, Hyderabad, Telangana, India.
Pravin Rao VadijeNewborn Unit, Fernandez Hospitals, Hyderabad, Telangana, 500029, India.
Fernandez Hospital · INRainbow Children's Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveComparison of mortality and major morbidities between very preterm (< 32 wk gestational age) small-for-gestational-age (SGA) and appropriate-for-gestational-age (AGA) neonates.

methodsA retrospective observational study of neonates born between 26-31 wk gestational age from January 2015 to December 2019 was done in level-3 neonatal intensive care unit of a high-risk perinatal center in South India.

resultsOf the 1,178 very preterm neonates born in the study period, 909 were eligible for inclusion. After propensity score matching for gestational age, gender, and antenatal steroid use, 592 (444 AGA and 148 SGA) were included in the final analysis. SGA neonates had increased odds of necrotizing enterocolitis (NEC) ≥ stage 2A [adjusted odds ratio (aOR): 2.2; 95% CI: 1.15-4.21], abnormal composite outcome, i.e., any one of the mortality or major morbidities (aOR: 2.99; 95% CI: 1.96-4.57), hypoglycemia requiring intravenous fluids (aOR: 2.11; 95% CI: 1.05-4.23), and anemia requiring blood transfusions (aOR: 3.13; 95% CI: 1.98-4.93); and a trend towards increased odds of bronchopulmonary dysplasia (aOR: 1.9, 95% CI: 0.92-3.91). Mortality, intraventricular hemorrhage ≥ grade 2, periventricular leukomalacia ≥ grade 2, and retinopathy of prematurity requiring treatment were not different.

conclusionsSGA neonates have higher odds of having NEC ≥ stage 2A, abnormal composite outcome, hypoglycemia, and anemia compared to appropriately grown neonates.

Indexed as

Infant, Extremely PrematureInfant, Premature, DiseasesFemaleGestational AgeHumansInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgePregnancyRetrospective StudiesIntrauterine growth restrictionMorbiditiesMortalitySmall for gestational age

Identifiers

PMID34324133
OpenAlexW3185210126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.