Evidence map›Paper›PMID 34324106›Full record

ArticleAntonie van Leeuwenhoek2021

Silver nanoparticles biosynthesized from secondary metabolite producing marine actinobacteria and evaluation of their biomedical potential.

Ashia Alam, Faouzia Tanveer, Ali Talha Khalil, Tanzeel Zohra, Saleh Khamlich, Muhammad Masroor Alam, Muhammad Salman, Muhammad Ali, Aamer Ikram, Zabta Khan Shinwari and 1 more

Abstract read
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Article in Antonie van Leeuwenhoek, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Phytogenic Silver Nanoparticles Derived fromBioengineering (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Green synthesis of silver nanoparticles byFrontiers in microbiology · 2025
    Article
  7. Article
  8. Article
  9. Overview on Strategies and Assays for Antibiotic Discovery.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  10. Review
  11. Journal of fungi (Basel, Switzerland) · 2022
    Article
  12. Frontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ashia Alam *Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
Faouzia Tanveer *Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
Ali Talha KhalilDepartment of Pathology, Lady Reading Hospital, Peshawar, Pakistan. alitalha.khalil@lrh.edu.pk.
Tanzeel ZohraPublic Health Laboratories Division, National Institute of Health, Islamabad, Pakistan.
Saleh KhamlichUNESCO UNISA Africa Chair in Nanosciences and Nanotechnology, College of Graduate Studies, University of South Africa, Pretoria, South Africa.
Muhammad Masroor AlamPublic Health Laboratories Division, National Institute of Health, Islamabad, Pakistan.
Muhammad SalmanPublic Health Laboratories Division, National Institute of Health, Islamabad, Pakistan.
Muhammad AliDepartment of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan. muhammad.ali@qau.edu.pk.ORCID http://orcid.org/0000-0002-7835-0663
Aamer IkramPublic Health Laboratories Division, National Institute of Health, Islamabad, Pakistan.
Zabta Khan ShinwariWHO Regional Reference Laboratory of Polio Eradication Initiative, National Institute of Health, Islamabad, Pakistan.
Malik MaazaUNESCO UNISA Africa Chair in Nanosciences and Nanotechnology, College of Graduate Studies, University of South Africa, Pretoria, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosynthesis of silver nanoparticles (AgNPs) from marine actinobacteria offers a promising avenue for exploring bacterial extracts as reducing and stabilizing agents. We report extracellular extracts of Rhodococcus rhodochrous (MOSEL-ME29) and Streptomyces sp. (MOSEL-ME28), identified by 16S rRNA gene sequencing for synthesis of AgNPs. Ultrafine silver nanoparticles were biosynthesized using the extracts of R. rhodochrous and Streptomyces sp. and their possible therapeutic applications were studied. The physicochemical properties of nanoparticles were established by HR-SEM/TEM, SAED, UV-Vis, EDS, XRD, and FTIR. UV-Vis spectra displayed characteristic absorption at 430 nm and 412 nm for AgNPs from Streptomyces sp. (S-AgNPs) and Rhodococcus sp. (R-AgNPs), respectively. HR-SEM/TEM, XRD, EDS analysis confirmed the spherical shape, crystalline nature, and elemental formation of silver. Crystallite or grain size was deduced as 5.52 nm for R-AgNPs and 35 nm for S-AgNPs. Zeta-potential indicated electrostatic negative charge for AgNPs, while FTIR revealed the presence of diverse functional groups. Disc diffusion assay indicated the broad-spectrum antibacterial potential of S-AgNPs with the maximum inhibition of B. subtilis while R-AgNPs revealed potency against P. aeruginosa at 10 µg/mL concentration. Biogenic AgNPs revealed antileishmanial activity and the IC

Indexed as

ActinobacteriaMetal NanoparticlesAnti-Bacterial AgentsMicrobial Sensitivity TestsPlant ExtractsRhodococcusRNA, Ribosomal, 16SSilverAnti-Bacterial AgentsPlant ExtractsRNA, Ribosomal, 16SSilverAntiviralBiomedical applicationsMarine actinobacteriaRhodococcus rhodochrousRhodococuss silver nanoparticles (R-AgNPs)StreptomycesStreptomyces silver nanoparticles (S-AgNPs

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.