Evidence map›Paper›PMID 34324102›Full record

Observational studyInternational ophthalmology2021

Post-remission retinal microvascular and choroidal thickness changes in eyes with Behḉet's disease posterior uveitis: an OCTA longitudinal study.

Amr Mohamed Abdelaziz Wassef, Mohamad Amr Salah Eddin Abdelhakim, Tamer Ahmed Macky, Karim Adly Raafat, Maha Mohamed Youssef

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amr Mohamed Abdelaziz WassefDepartment of Ophthalmology, Kasr Al Ainy Hospital, Cairo University, El Saray Street, Manial, Cairo, 11956, Egypt. amrwassef5_2@yahoo.com.ORCID http://orcid.org/0000-0001-6193-7276
Mohamad Amr Salah Eddin AbdelhakimDepartment of Ophthalmology, Kasr Al Ainy Hospital, Cairo University, El Saray Street, Manial, Cairo, 11956, Egypt.
Tamer Ahmed MackyDepartment of Ophthalmology, Kasr Al Ainy Hospital, Cairo University, El Saray Street, Manial, Cairo, 11956, Egypt.
Karim Adly RaafatDepartment of Ophthalmology, Kasr Al Ainy Hospital, Cairo University, El Saray Street, Manial, Cairo, 11956, Egypt.
Maha Mohamed YoussefDepartment of Ophthalmology, Kasr Al Ainy Hospital, Cairo University, El Saray Street, Manial, Cairo, 11956, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the retinal microvascular and choroidal thickness changes in eyes with active Behḉet's disease posterior uveitis and post-remission. PATIENTS AND

methodsA prospective longitudinal observational analytic study where patients with active Behḉet's posterior uveitis (BU) were assessed by optical coherence tomography angiography (OCTA) and enhanced depth imaging OCT during activity and after remission, for retinal microvascular and subfoveal choroidal thickness (SFCT) changes.

results26 eyes of 20 patients were included. With remission of active posterior uveitis, capillary density in both layers increased, only being significant in the superficial capillary plexus (SCP) 1.81 ± 3.57% (p = 0.025), while the foveal avascular zone (FAZ) area increased by 0.036 ± 0.069 mm (p = 0.023).

conclusionOCTA can be used to monitor the activity of Behḉet's posterior uveitis. Comparing the retinal microvascular changes during activity and after remission, the superficial capillary plexus was found to be more indicative of the activity status, while the deep capillary plexus and foveal avascular zone area-being more irreversible-are more useful as prognostic indicators. Subfoveal choroidal thickness, on the other hand, proved to be a consistent indictor of visual function; however, its change doesn't accurately reflect the activity status.

Indexed as

Behcet SyndromeUveitis, PosteriorFluorescein AngiographyHumansLongitudinal StudiesProspective StudiesRetinal VesselsTomography, Optical CoherenceBehḉet’s diseaseCapillary plexus densityChoroidal thicknessEnhanced depth imagingFoveal avascular zoneOptical coherence tomography angiographyUveitis

Identifiers

PMID34324102
OpenAlexW3185090945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.