Evidence map›Paper›PMID 34324048›Full record

ReviewSchmerz (Berlin, Germany)2021

[Pain management during pregnancy : An expert-based interdisciplinary consensus recommendation].

Daniela Marhofer, Wolfgang Jaksch, Thomas Aigmüller, Stefan Jochberger, Berndt Urlesberger, Katharina Pils, Barbara Maier, Rudolf Likar, Beate Kayer, Roswitha Wallner and 2 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Schmerz (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Overview of Research on Essential Oils ofPharmaceuticals (Basel, Switzerland) · 2026
    Review
  4. Understanding a Potential Role for the NLRP3 Inflammasome in Placenta-Mediated Pregnancy Complications.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniela MarhoferAllgemeine Intensivmedizin und Schmerztherapie, Medizinische Universität Wien, Universitätsklinik für Anästhesie, Spitalgasse 23, 1090, Wien, Österreich. daniela.marhofer@meduniwien.ac.at.
Wolfgang JakschAbteilung für Anästhesie, Intensiv- und Schmerzmedizin, Wiener Gesundheitsverbund, Klinik Ottakring, Wien, Österreich.
Thomas AigmüllerAbteilung für Gynäkologie und Geburtshilfe, Landeskrankenhaus Hochsteiermark - Standort Leoben, Leoben, Österreich.
Stefan JochbergerUniversitätsklinik für Anästhesie und Intensivmedizin, Medizinische Universität Innsbruck, Innsbruck, Österreich.
Berndt UrlesbergerUniversitätsklinik für Kinder- und Jugendheilkunde, Klinische Abteilung für Neonatologie, Medizinische Universität Graz, Graz, Österreich.
Katharina PilsInstitut für Physikalische Medizin und Rehabilitation, Wiener Gesundheitsverbund, Klinik Landstraße, Wien, Österreich.
Barbara MaierGynäkologisch-Geburtshilfliche Abteilung, Wiener Gesundheitsverbund, Klinik Ottakring, Wien, Österreich.
Rudolf LikarAbteilung für Anästhesiologie und Intensivmedizin, Klinikum Klagenfurt am Wörthersee, Klagenfurt, Österreich.
Beate KayerFachbereich Hebammen, Fachhochschule Campus Wien, Wien, Österreich.
Roswitha WallnerFachbereich Hebammen, Fachhochschule Campus Wien, Wien, Österreich.
Petra FinkAbteilung für Anästhesiologie und Intensivmedizin, Landesklinikum Amstetten, Amstetten, Österreich.
Gabriele GröglAbteilung für Anästhesie und Operative Intensivmedizin, Wiener Gesundheitsverbund, Klinik Landstraße, Wien, Österreich.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnancy and pain of different origins is an unfavorable combination that presents all practitioners with special challenges. Pain negatively affects the homeostasis of humans. Patient compliance and in-depth knowledge of the fetotoxicity and teratogenicity of the substances are necessary to maintain a balance between therapy for the mother and safety of the unborn child.

objectivesExperts from various disciplines who are entrusted with the care of pregnant patients with pain have come together to develop drug and nondrug therapy concepts with the aim of providing adequate analgesia for pregnant pain patients. MATERIALS AND

methodsRelevant questions were formulated by experts and subjected to a literature search. Combined with further national and international recommendations, treatment concepts were developed and discussed in an interdisciplinary manner. Core statements were then drawn up and given recommendation grades.

resultsDepending on the trimester, paracetamol, ibuprofen, diclofenac, metamizole, and opioids can be administered carefully in the event of pain; special care is required with nonsteroidal anti-inflammatory drugs (NSAIDs ) in the last trimester. COX‑2 inhibitors are not recommended. For neuropathic pain, amitriptyline, duloxetine, and venlafaxine are considered safe. Non-pharmacological treatment concepts are also available, namely transcutaneous electrical nerve stimulation (TENS therapy), kinesio tapes, and acupuncture. Lymphatic drainage is recommended in cases of edema, if not caused by preeclampsia.

conclusionsA deliberated concept for pain therapy during pregnancy should be initiated with a non-pharmacological intervention and, if necessary, supplemented with pharmacological agents.

Indexed as

NeuralgiaPain ManagementAcetaminophenAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalChildFemaleHumansPregnancyAcetaminophenAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalAcute painChronic painMigraineNeuropathic painObstetrical

Identifiers

PMID34324048
PMCPMC8613155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.