Evidence map›Paper›PMID 34323661›Full record

ArticleOrganogenesis2021

Osteogenic and Angiogenic Synergy of Human Adipose Stem Cells and Human Umbilical Vein Endothelial Cells Cocultured in a Modified Perfusion Bioreactor.

Fatemeh Mokhtari-Jafari, Ghasem Amoabediny, Mohammad Mehdi Dehghan, Sonia Abbasi Ravasjani, Massoumeh Jabbari Fakhr, Yasaman Zamani

Open access · bronzeAbstract read
In one paragraph

Article in Organogenesis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fatemeh Mokhtari-JafariSchool of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran.ORCID 0000-0003-4367-6468
Ghasem AmoabedinySchool of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
Mohammad Mehdi DehghanDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Sonia Abbasi RavasjaniDepartment of Biomedical Engineering, Research Center for New Technologies in Life Science Engineering, University of Tehran, Tehran, Iran.
Massoumeh Jabbari FakhrDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.ORCID 0000-0001-7279-2447
Yasaman ZamaniDepartment of Biomedical Engineering, Research Center for New Technologies in Life Science Engineering, University of Tehran, Tehran, Iran.ORCID 0000-0002-3687-2471
University of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synergistic promotion of angiogenesis and osteogenesis in bone tissue-engineered constructs remains a crucial clinical challenge, which might be overcome by simultaneous employment of superior techniques including coculture systems, differentiation-stimulated factors, combinatorial scaffolds and bioreactors.Current study investigated the effect of flow perfusion along with coculture of human adipose stem cells (hASCs) and human umbilical vein endothelial cells (HUVECs) on osteogenic and angiogenic differentiation.Pre-treated hASCs with 1,25-dihydroxyvitamin D

Indexed as

OsteogenesisStem CellsBioreactorsCell DifferentiationCells, CulturedCoculture TechniquesHumansHuman Umbilical Vein Endothelial CellsPerfusionTissue Scaffoldsangiogenic differentiationbonehuman adipose stem cellshuman umbilical vein endothelial cellsmodified perfusion bioreactorosteogenic differentiation

Identifiers

PMID34323661
PMCPMC9208766
OpenAlexW3183390686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.