Evidence map›Paper›PMID 34323639›Full record

ArticlePsychological science2021

Are Sex Differences in Human Brain Structure Associated With Sex Differences in Behavior?

Liza van Eijk, Dajiang Zhu, Baptiste Couvy-Duchesne, Lachlan T Strike, Anthony J Lee, Narelle K Hansell, Paul M Thompson, Greig I de Zubicaray, Katie L McMahon, Margaret J Wright and 1 more

Abstract read
In one paragraph

Article in Psychological science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Brain regional susceptibility to tauopathy in individuals at risk for chronic traumatic encephalopathy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Testing the extreme male brain hypothesis: Is autism spectrum disorder associated with a more male-typical brain?Autism research : official journal of the International Society for Autism Research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Liza van EijkCentre for Psychology and Evolution, School of Psychology, University of Queensland.ORCID 0000-0001-8254-1019
Dajiang ZhuDepartment of Computer Science and Engineering, The University of Texas at Arlington.
Baptiste Couvy-DuchesneInstitute for Molecular Bioscience, University of Queensland.
Lachlan T StrikeQueensland Brain Institute, University of Queensland.
Anthony J LeeDivision of Psychology, University of Stirling.ORCID 0000-0001-8466-2594
Narelle K HansellQueensland Brain Institute, University of Queensland.
Paul M ThompsonImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California.
Greig I de ZubicarayInstitute of Health and Biomedical Innovation, Queensland University of Technology.ORCID 0000-0003-4506-0579
Katie L McMahonHerston Imaging Research Facility and School of Clinical Sciences, Queensland University of Technology.ORCID 0000-0002-6357-615X
Margaret J WrightQueensland Brain Institute, University of Queensland.
Brendan P ZietschCentre for Psychology and Evolution, School of Psychology, University of Queensland.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Training U54EB020403 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2018
$10.1M
ENIGMA World Aging CenterR01AG058854 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2021 to 2025
$3.3M
Genetic influences on the brain: A twin imaging studyR01HD050735 · NICHD · QUEENSLAND INSTITUTE OF MEDICAL RESEARCH · PI WRIGHT, MARGARET JANE · 2007 to 2011
$2.6M
ENIGMA-SD: Understanding Sex Differences in Global Mental Health through ENIGMAR01MH116147 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2018 to 2021
$2.5M
ENIGMA World Aging CenterR56AG058854 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2018 to 2018
$683k
NIA NIH HHS R01 AG058854NIA NIH HHS R56 AG058854NIBIB NIH HHS P41 EB015922NIBIB NIH HHS P41 EB027061NIBIB NIH HHS U54 EB020403NICHD NIH HHS R01 HD050735NIMH NIH HHS R01 MH116147NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

On average, men and women differ in brain structure and behavior, raising the possibility of a link between sex differences in brain and behavior. But women and men are also subject to different societal and cultural norms. We navigated this challenge by investigating variability of sex-differentiated brain structure within each sex. Using data from the Queensland Twin IMaging study (

Indexed as

ConnectomeSex CharacteristicsBrainFemaleHumansMagnetic Resonance ImagingMaleTwinsbrain structuremasculinizationMRIneuroimagingopen datatwin modeling

Identifiers

PMID34323639
PMCPMC8726594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.