Evidence map›Paper›PMID 34323598›Full record

ArticleEpigenomics2021

DNA methylation differences in cortical grey and white matter in schizophrenia.

Amber Berdenis van Berlekom, Nina Notman, Marjolein Am Sneeboer, Gijsje Jlj Snijders, Lotte C Houtepen, Danny M Nispeling, Yujie He, Stella Dracheva, Elly M Hol, René S Kahn and 3 more

Open access · greenAbstract read
In one paragraph

Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Amber Berdenis van BerlekomDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-7546-0250
Nina NotmanDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Marjolein Am SneeboerDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Gijsje Jlj SnijdersDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-2694-1234
Lotte C HoutepenDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Danny M NispelingDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Yujie HeDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Stella DrachevaMental Illness Research, Education, & Clinical Center (VISN 2 South), James J Peters VA Medical Center, Bronx, NY 10468, USA.ORCID 0000-0001-5917-8688
Elly M HolDepartment of Translational Neuroscience, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
René S KahnDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Lot D de WitteDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Marco P BoksDepartment of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0001-6163-7484
Psychiatric Donor Program of the Netherlands Brain Bank (NBB-PSY)Psychiatric Donor Program of The Netherlands Brain Bank (NBB-PSY), Amsterdam, The Netherlands.
Utrecht University · NLIcahn School of Medicine at Mount Sinai · USJames J. Peters VA Medical Center · US

Funding

The 3D genome in transcriptional regulation across the postnatal life span, with implications for schizophrenia and bipolar disorderU01MH116442 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AKBARIAN, SCHAHRAM, DRACHEVA, STELLA · 2018 to 2022
$5.9M
Neuronal Subtype Specific Epigenetic Regulation in SchizophreniaI01BX002876 · VA · JAMES J PETERS VA MEDICAL CENTER · PI DRACHEVA, STELLA · 2016 to 2020
–
BLRD VA I01 BX002876NIMH NIH HHS U01 MH116442
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA MethylationGene Expression RegulationAgedAged, 80 and overCase-Control StudiesEpigenesis, GeneticEpigenomicsFemaleGray MatterHumansMaleMiddle AgedSchizophreniaWhite MatterDNA-methylationpostmortemschizophrenia

Identifiers

PMID34323598
PMCPMC8386513
OpenAlexW3184325487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.