Evidence map›Paper›PMID 34323468›Full record

ArticleACS biomaterials science & engineering2021

Biodegradable, Tissue Adhesive Polyester Blends for Safe, Complete Wound Healing.

John L Daristotle, Metecan Erdi, Lung W Lau, Shadden T Zaki, Priya Srinivasan, Manogna Balabhadrapatruni, Omar B Ayyub, Anthony D Sandler, Peter Kofinas

Open access · greenAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Application of PLCL as a biodegradable polymer in biomedical engineering.Journal of materials science. Materials in medicine · 2026
    Review
  2. Review
  3. Review
  4. Degradable polymer bone adhesives.Fundamental research · 2025
    Review
  5. Vitamin E incorporated in Carboxymethyl Cellulose-Gelatin Hydrogel Increases Wound Healing.International journal of molecular and cellular medicine · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Polymer nanomaterials for use as adjuvant surgical tools.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

John L DaristotleFischell Department of Bioengineering, University of Maryland, 3102 A. James Clark Hall, 8278 Paint Branch Dr., College Park, Maryland 20742, United States.ORCID 0000-0002-3523-5390
Metecan ErdiDepartment of Chemical and Biomolecular Engineering, University of Maryland, 4418 Stadium Dr., College Park, Maryland 20742, United States.ORCID 0000-0001-9267-654X
Lung W LauSheikh Zayed Institute for Pediatric Surgical Innovation, Joseph E. Robert Jr. Center for Surgical Care, Children's National Medical Center, 111 Michigan Avenue NW, Washington, District of Columbia 20010, United States.
Shadden T ZakiDepartment of Materials Science and Engineering, University of Maryland, 4418 Stadium Dr., College Park, Maryland 20742, United States.
Priya SrinivasanSheikh Zayed Institute for Pediatric Surgical Innovation, Joseph E. Robert Jr. Center for Surgical Care, Children's National Medical Center, 111 Michigan Avenue NW, Washington, District of Columbia 20010, United States.
Manogna BalabhadrapatruniDepartment of Chemical and Biomolecular Engineering, University of Maryland, 4418 Stadium Dr., College Park, Maryland 20742, United States.
Omar B AyyubDepartment of Chemical and Biomolecular Engineering, University of Maryland, 4418 Stadium Dr., College Park, Maryland 20742, United States.
Anthony D SandlerSheikh Zayed Institute for Pediatric Surgical Innovation, Joseph E. Robert Jr. Center for Surgical Care, Children's National Medical Center, 111 Michigan Avenue NW, Washington, District of Columbia 20010, United States.
Peter KofinasDepartment of Chemical and Biomolecular Engineering, University of Maryland, 4418 Stadium Dr., College Park, Maryland 20742, United States.ORCID 0000-0001-6657-3037
University of Maryland, College Park · USChildren's National · US

Funding

Sprayable Polymer Blends for Prevention of Site Specific Surgical AdhesionsR01GM141132 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI KOFINAS, PETER · 2022 to 2025
$1.6M
Direct Deposition of Polymer Fibers for Use as a Surgical SealantR01EB019963 · NIBIB · UNIV OF MARYLAND, COLLEGE PARK · PI KOFINAS, PETER, SANDLER, ANTHONY D. · 2016 to 2019
$1.5M
Biodegradable Polymer Surgical Sealant with Increased Adhesion and Reduced InflammationF31EB025735 · NIBIB · UNIV OF MARYLAND, COLLEGE PARK · PI DARISTOTLE, JOHN LOUIS · 2018 to 2019
$42k
NIBIB NIH HHS F31 EB025735NIBIB NIH HHS R01 EB019963NIGMS NIH HHS R01 GM141132
6 · The paper itself

Abstract

Pressure-sensitive adhesives typically used for bandages are nonbiodegradable, inhibiting healing, and may cause an allergic reaction. Here, we investigated the effect of biodegradable copolymers with promising thermomechanical properties on wound healing for their eventual use as biodegradable, biocompatible adhesives. Blends of low molecular weight (LMW) and high molecular weight (HMW) poly(lactide-

Indexed as

Tissue AdhesivesAdhesivesBandagesPolyestersWound HealingAdhesivesPolyestersTissue Adhesivesbandagebiodegradable adhesivesprayable polymertissue adhesionwound healing

Identifiers

PMID34323468
PMCPMC8594560
OpenAlexW3186272611

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.