Evidence map›Paper›PMID 34323417›Full record

ArticleClinical and translational medicine2021

Deleted in malignant brain tumor 1 genetic variation confers urinary tract infection risk in children and mice.

David S Hains, Shamik Polley, Dong Liang, Vijay Saxena, Samuel Arregui, John Ketz, Evan Barr-Beare, Ashley Rawson, John D Spencer, Ariel Cohen and 7 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Urinary tract infections in children.Nature reviews. Urology · 2026
    Review
  2. Life science alliance · 2024
    Article
  3. A Common Polymorphism inInternational journal of molecular sciences · 2024
    Article
  4. Uropathogen and host responses in pyelonephritis.Nature reviews. Nephrology · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

David S HainsDepartment of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
Shamik PolleyDepartment of Genetics and Genome Biology, University of Leicester, Leicester, UK.
Dong LiangDepartment of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
Vijay SaxenaDepartment of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
Samuel ArreguiDepartment of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
John KetzThe Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Evan Barr-BeareBrown University, Providence, Rhode Island, USA.
Ashley RawsonDepartment of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
John D SpencerThe Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Ariel CohenThe Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Pernille L HansenLundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.
Martina TuttolomondoLundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.
Cinzia CasellaLundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.
Henrik J DitzelLundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.
Daniel CohenEmergency Department, Nationwide Children's Hospital, Columbus, Ohio, USA.
Edward J HolloxDepartment of Genetics and Genome Biology, University of Leicester, Leicester, UK.
Andrew L SchwadererDepartment of Pediatrics, Indiana University, Indianapolis, Indiana, USA.ORCID 0000-0003-0560-4666

Funding

The Contributions of Ribonuclease 4 & 7 to Urinary Tract Antibacterial DefenseR01DK115737 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI John David Spencer · 2018 to 2026
$2.8M
The interface between critical acid-base mediators and the renal bacterial defenseR01DK106286 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI HAINS, DAVID SULLIVAN, SCHWADERER, ANDREW LAWRENCE · 2015 to 2018
$1.6M
Genetic Variations and Development of Vesicoureteral Reflux and SequelaeRC4DK090937 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI HAINS, DAVID SULLIVAN, SCHWADERER, ANDREW LAWRENCE · 2010 to 2010
$1.5M
NIDDK NIH HHS R01 DK106286NIDDK NIH HHS R01 DK115737NIDDK NIH HHS RC4 DK090937
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsCalcium-Binding ProteinsCase-Control StudiesChildDisease Models, AnimalDNA-Binding ProteinsDNA Copy Number VariationsGenetic Predisposition to DiseaseHumansMiceMice, KnockoutRisk FactorsTumor Suppressor ProteinsUrinary TractUrinary Tract InfectionsAnti-Bacterial AgentsCalcium-Binding ProteinsDMBT1 protein, humanDmbt1 protein, mouseDNA-Binding ProteinsTumor Suppressor Proteins

Identifiers

PMID34323417
PMCPMC8255058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.