Evidence map›Paper›PMID 34323401›Full record

ArticleClinical and translational medicine2021

A natural DYRK1A inhibitor as a potential stimulator for β-cell proliferation in diabetes.

Mengzhu Zheng, Qingzhe Zhang, Chengliang Zhang, Canrong Wu, Kaiyin Yang, Zhuorui Song, Qiqi Wang, Chen Li, Yirong Zhou, Jiachun Chen and 2 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Hyperglycemia activates FGFR1Acta pharmaceutica Sinica. B · 2024
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Mengzhu ZhengHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qingzhe ZhangHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chengliang ZhangHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Canrong WuHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Kaiyin YangHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhuorui SongWuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Qiqi WangWuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Chen LiWuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Yirong ZhouHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiachun ChenHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hua LiHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji-Rongcheng Center for Biomedicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0003-1903-836X
Lixia ChenWuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
Huazhong University of Science and Technology · CNShenyang Pharmaceutical University · CNTongji Hospital · CN

Funding

China Postdoctoral Science Foundation 2020T130039ZXChunhui Program-Cooperative Research Project of the Ministry of EducationFundamental Research Fund for the Central Universities 2017KFYXJJ151Liaoning Province Natural Science Foundation 2020-MZLH-31Liaoning Revitalization Talents Program XLYC1807182National Natural Science Foundation of China 81773594National Natural Science Foundation of China 81773637National Natural Science Foundation of China 81773869National Natural Science Foundation of China U1803122Wuhan COVID-19 Rapid Response Call Fund EX20C02
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

SwertiaAnimalsCell ProliferationDiabetes MellitusDyrk KinasesHumansInsulin-Secreting CellsMicePlant ExtractsProtein Serine-Threonine KinasesProtein-Tyrosine KinasesXanthenesdesmethylbellidifolinDyrk KinasesPlant ExtractsProtein Serine-Threonine KinasesProtein-Tyrosine KinasesXanthenes

Identifiers

PMID34323401
PMCPMC8288015
OpenAlexW3183846514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.